Effects of Epidural Anesthesia and Analgesia on Postoperative Metabolic, Immune Function and Hemodynamic Changes of Open Liver Resection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Clinical outcomes during and after open liver resection
研究概览
简要总结
The purpose of this study is to analyze the effects of epidural anesthesia and analgesia on intraoperative clinical outcome, postoperative recovery, metabolic changes, and immune functions of the patients receiving open liver resection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •left hemihepatectomy left lateral sectionectomy clinical diagnosis of hepatolithiasis
排除标准
- •abnormal coagulation tests diabetes mellitus significant cirrhosis
结局指标
主要结局
Clinical outcomes during and after open liver resection
时间窗: participants will be followed for the duration of hospital stay, an expected average of 4 weeks
intraoperative outcome including operation time, liver resection time, estimated blood loss, urine output, etc during operation. PACU recovery, pain score, liver and gastrointestinal function, hospital stay time,etc assessed. Before operation, right after operation(0), and 3hr, 12hr, 24hr, 72hrs after operation, blood glucose and insulin was measured.
次要结局
- Cytokine change in perioperation of open liver resection(Before operation, within 5 days after operation)
研究者
Chun-Yan Yan
M.D. , Ph.D
Sir Run Run Shaw Hospital