Effects of Epidural Anesthesia and Analgesia on Postoperative Metabolic, Immune Function and Hemodynamic Changes of Open Liver Resection
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Hepatectomy
- Sponsor
- Sir Run Run Shaw Hospital
- Enrollment
- 26
- Locations
- 1
- Primary Endpoint
- Clinical outcomes during and after open liver resection
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
The purpose of this study is to analyze the effects of epidural anesthesia and analgesia on intraoperative clinical outcome, postoperative recovery, metabolic changes, and immune functions of the patients receiving open liver resection.
Investigators
Chun-Yan Yan
M.D. , Ph.D
Sir Run Run Shaw Hospital
Eligibility Criteria
Inclusion Criteria
- •left hemihepatectomy left lateral sectionectomy clinical diagnosis of hepatolithiasis
Exclusion Criteria
- •abnormal coagulation tests diabetes mellitus significant cirrhosis
Outcomes
Primary Outcomes
Clinical outcomes during and after open liver resection
Time Frame: participants will be followed for the duration of hospital stay, an expected average of 4 weeks
intraoperative outcome including operation time, liver resection time, estimated blood loss, urine output, etc during operation. PACU recovery, pain score, liver and gastrointestinal function, hospital stay time,etc assessed. Before operation, right after operation(0), and 3hr, 12hr, 24hr, 72hrs after operation, blood glucose and insulin was measured.
Secondary Outcomes
- Cytokine change in perioperation of open liver resection(Before operation, within 5 days after operation)