Effect of Epidural Anesthesia and Analgesia on Patients' Outcomes After Liver Resection

Not Applicable

Completed

• Conditions: Hepatectomy

• Registration Number: NCT01617811
• Lead Sponsor: Sir Run Run Shaw Hospital

Brief Summary

The purpose of this study is to analyze the effects of epidural anesthesia and analgesia on intraoperative clinical outcome, postoperative recovery, metabolic changes, and immune functions of the patients receiving open liver resection.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08
• Primary Completion: 2008-12
• Study Completion: 2008-12
• Status Verified: 2012-06
• Study First Submitted: 2012-06-05
• Study First Submitted QC: 2012-06-09
• Last Update Submitted: 2012-06-09
• Study First Posted: 2012-06-12
• Last Update Posted: 2012-06-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• left hemihepatectomy left lateral sectionectomy clinical diagnosis of hepatolithiasis

Exclusion Criteria

• abnormal coagulation tests diabetes mellitus significant cirrhosis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Clinical outcomes during and after open liver resection	participants will be followed for the duration of hospital stay, an expected average of 4 weeks	intraoperative outcome including operation time, liver resection time, estimated blood loss, urine output, etc during operation. PACU recovery, pain score, liver and gastrointestinal function, hospital stay time,etc assessed.; Before operation, right after operation(0), and 3hr, 12hr, 24hr, 72hrs after operation, blood glucose and insulin was measured.

Secondary Outcome Measures

Name	Time	Method
Cytokine change in perioperation of open liver resection	Before operation, within 5 days after operation	Before operation and 0, 3hr, 12hr, 24hr, D3, D5 after operation, serum IL-1β, IFN-γ, IL-4, IL-10 and TGF-β by microassay.

Trial Locations

Locations (1)

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University; 🇨🇳 Hangzhou, Zhejiang, China