Imaging of Retinochoroidal Vasculature in Patients Being Assessed for Cardiovascular Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 2
- 主要终点
- Correlation with and prediction of the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography
研究概览
简要总结
This study aims to determine whether changes in retinal vasculature seen on SS-OCTA can be correlated to degree of cardiovascular disease as measured by carotid duplex ultrasonography.
详细描述
The study's primary objective is to determine whether measures taken from SS-OCTA, color fundus photography, and retinal exams can correlate with and predict the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography by examining the following parameters: retinal vessel caliber, retinal vessel density, retinal vessel perfusion, retinal vessel tortuosity, presence of Hollenhorst or other plaques, and/or areas of ischemia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects between 18 and 95 years of age
- •Able to participate in a clinical eye examination setting
- •Able to consent
- •Subjects receiving standard of care carotid duplex ultrasounds
排除标准
- •Inability to get high quality imaging for any reason (ex. Dense cataract, media opacity)
- •Lack of capacity to provide informed consent
- •Subjects younger than 18 years of age or older than 95 years of age
- •History of stroke or acute loss of vision
- •Unable to participate in a clinical eye examination setting
研究组 & 干预措施
All Participants
50 participants identified in the Northwestern Medicine Division of Vascular Surgery.
干预措施: Swept Source Optical Coherence Tomography Angiography (Diagnostic Test)
结局指标
主要结局
Correlation with and prediction of the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography
时间窗: 2 hours
Determining whether measures taken from SS-OCTA, color fundus photography, and retinal exams can correlate with and predict the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography by examining the following parameters: retinal vessel caliber, retinal vessel density, retinal vessel perfusion, retinal vessel tortuosity, presence of Hellenhorst or other plaques, and/or areas of ischemia.
次要结局
未报告次要终点
研究者
Rukhsana Mirza
Principal Investigator, M.D., MS
Northwestern University