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Natural Orifice Translumenal Endoscopic Surgery: Laparoscopic-Assisted Transvaginal Cholecystectomy

Phase 1
Terminated
Conditions
Cholelithiasis
Registration Number
NCT00910325
Lead Sponsor
Massachusetts General Hospital
Brief Summary

To determine the feasibility, safety, and efficacy of a novel minimally invasive approach to cholecystectomy and to establish a description of this novel translumenal technique in humans at this institution.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
Female
Target Recruitment
3
Inclusion Criteria
  • Females who are postmenopausal or who no longer wish to bear children
  • Females >25 years old and <65 years old
  • Diagnosis of biliary disease requiring cholecystectomy
  • American Society of Anesthesiology (ASA) Class I or II
  • Females who are able to understand and willing to sign an informed consent document
Exclusion Criteria
  • Pregnancy
  • BMI >= 30
  • Patients who are still interested in childbearing
  • Patients taking immunosuppressive medications or who are immunocompromised
  • Patients with acute cholecystitis or history of acute cholecystitis ( as defined by right upper quadrant pain with history of fevers and/or elevated white blood cell count and/or positive ultrasound findings, ie, gallbladder wall thickening or pericholecystic fluid)
  • Patients with suspicion of gallbladder cancer
  • Patients with history of previous open abdominal surgery
  • Patients with untreated common bile duct stones

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
The safety and efficacy of the procedureone year
Secondary Outcome Measures
NameTimeMethod
Post-operative painone year
Time to return to workone year
Time to return to daily activitiesone year

Trial Locations

Locations (1)

Massachusetts General Hospital

🇺🇸

Boston, Massachusetts, United States

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