Comparative Effects of Sensory Re-education and Neural Mobilization in CTS Patients

Not Applicable

Not yet recruiting

• Conditions: Carpal Tunnel Syndrome (CTS)

• Registration Number: NCT06686212
• Lead Sponsor: Riphah International University

Brief Summary

The aim of study is to compare the effects of sensory re-education and neural mobilization in CTS patients.

Detailed Description

This study will be randomized clinical trial that will be conducted at Services Hospital Lahore and Government Teaching Hospital Shahdara. In this study 48 participants with CTS will be included as per sample size calculation through non-probability convenience sampling technique. Participants that achieve the required standards of inclusion and exclusion criteria will be randomly allocated using online randomization tool into two groups. Group A will receive Sensory Re-education therapy, strengthening exercises and Kinesio taping for 60 minutes, Group B will be given neural mobilization techniques, strengthening exercises and Kinesio taping for 60 minutes with short rest intervals. Both treatments will be given 3 days per week for 12 weeks.

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Status Verified: 2024-11
• Study Start: 2024-11-10
• Study First Submitted: 2024-11-12
• Study First Submitted QC: 2024-11-12
• Last Update Submitted: 2024-11-12
• Study First Posted: 2024-11-13
• Last Update Posted: 2024-11-13
• Primary Completion: 2025-07-30
• Study Completion: 2025-07-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Patients of both genders age 20-50 years with mild and moderate carpal tunnel syndrome.
• Patients having positive score on CTS specific test (Phalen's test and Tinel's test).
• Patients with pain, paresthesia and hyperesthesia at the course of median nerve.
• Patients that are clinically diagnosed with carpal tunnel syndrome by physician. Patients having BMI >25 (kg/m2).

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Exclusion Criteria

• Patients with polyneuropathies.
• Patients with carpal tunnel syndrome due to any systemic illness (diabetes mellitus, thyroid diseases and R.A).

Patients having cervical radiculopathy.

Patients with history of wrist fracture.

Patients getting steroid injections and after CTS surgery.

Obese and pregnant female with carpal tunnel syndrome.

Patients with any cognitive or neurological problems are excluded from study.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Numerical pain rating scale	12th week	The NPRS is use to capture the patient's level of pain. Patients are allowed to indicate the intensity of their current pain level using an 11-point scale, ranging from 0 (no pain) to 10 (worst pain imaginable).
Boston Carpal Tunnel Questionnaire	12th week	A patient self-reported questionnaire includes 2 sub scales: The Symptom Severity Scale (SSS), which comprise 11 questions and uses a 5- point Likert scale; and the Functional Status Scale (FSS) having 8 items, which have to be evaluated for degree of difficulty on a 5-point Likert scale. Each scale generates a final score (sum of scores divided by number of items), which ranges from 1 to 5, with a higher score predicting greater disability.
Hand Held Dynamometer	12th week	Hand grip strength is measured using a handheld dynamometer. Patients are asked to grip the dynamometer isometrically and advised to grip it as hard as they can. Readings will be taken in pounds lb. The average value of 3 trials is recorded.
Pinch gauge meter	12th week	Tip pinch grip strength will be assessed using a manual dynamometer (pinch gauge meter). Participants asked to perform a maximal pinch grip by pressing the gauge between the tip of their thumb and index finger. The average of three trials will calculated and defined as the maximal tip pinch grip strength measured in kilograms.