Cortical and Functional Responses to an Early Protocol of Sensory Re-education of the Hand Using Audio-tactile Interaction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17
- 主要终点
- Sensory Threshold - Mann Whitney non-parametric test
研究概览
简要总结
The implementation of early sensory re-education (SR) techniques, aimed to preserve the cortical hand area, such as the use of audio-tactile interaction, becomes an important strategy to obtain also a better sensory function. The aim of this study was to investigate sensory function outcomes (threshold monofilaments, two-point discrimination test, STI and DASH) and cortical responses (fMRI) in patients submitted to an early protocol of SR of the hand with a sensor glove model. After surgical repair of median and/or ulnar nerves, 17 participants were divided into two groups: the training group, trained on the protocol with the sensor glove model, and the control group, untrained. After six-month follow-up, no difference was observed between groups, related to sensory function, especially tactile gnosis. Despite this, the early training with this sensor glove model seems to provide some type of cortical audio-tactile interaction, contributing to previous studies that focus in early SR of the hand using the integration of different sensory modalities.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Injury of the ulnar and/or median nerves at the wrist or distal forearm level surgically repaired
排除标准
- •Neurological diseases
- •Systemic diseases, which affected either directly or indirectly the central or peripheral nervous system
- •Extensive traumas in the upper limbs
结局指标
主要结局
Sensory Threshold - Mann Whitney non-parametric test
时间窗: First, Third and Sixth month post-operative
Sensory Threshold was assessed by esthesiometry at first, third and sixth month post-operative
Tactil Gnosis - Mann Whitney non-parametric test
时间窗: First, Third and Sixth month post-operative
Tactile Gnosis was assessed by Two-point discrimination and Shape and Texture Identification Test at first, third and sixth month post-operative
Cortical responses - fMRI data analysed by Granger Causality Map
时间窗: Three months
Training group subjects were submitted to fMRI exam at third month post-operative
Self-report function - Mann Whitney non-parametric test
时间窗: First, Third and Sixth month post-operative
Self-report function was assessed by DASH questionnaire at first, third and sixth month post-operative
次要结局
未报告次要终点
研究者
Marisa de Cassia Registro Fonseca
Collaborator
University of Sao Paulo