JPRN-jRCT2080221507未知1 期
A multicenter, open-label, non-randomized, dose-escalation, therapeutic exploratory trial to evaluate the safety and efficacy of OPB-31121 in patients with progressive hepatocellular carcinoma
试验速览
- 阶段
- 1 期
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 80age old（—）
- 性别
- All
入选标准
- •1) Patients with histopathologically or clinically confirmed diagnosis of hepatocellular carcinoma
- •2) Patients with Child-Pugh classification A or B
- •3) Patients unresponsive to standard therapy or for whom standard therapy is intolerable, or for whom there is no appropriate therapy
- •4) Patients who are able to take oral medication
- •5) Patients age 20 to 79 years (inclusive) at time of informed consent
- •6) Patients with an ECOG performance status score of 0-2
- •7) Patients have the eligible organ function in screening visit
排除标准
- •1) Patients with a primary malignant tumor
- •2) Patients with a history of liver transplant
- •3) Patients with brain metastases
- •4) Patients with a complication of uncontrolled
- •5) Patients with a psychiatric disorder that might cause difficulty in obtaining informed consent or in conducting the trial
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