Articulation and Coordination of Speech in Parkinson*s Disease
Completed
- Conditions
- Parkinson's disease10028037
- Registration Number
- NL-OMON45931
- Lead Sponsor
- Rijksuniversiteit Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
- At least 18 years of age
- Mother tongue speaker of Dutch;Only for the PD group:
- Diagnosed with idiopathic Parkinson*s disease (according to the UK Parkinson*s Disease Society Brain Bank Clinical Diagnostic Criteria)
Exclusion Criteria
- Older than 80 years of age
- A score of 2 or higher on part 1.1 (cognitive impairment) or part 1.2 (hallucinations and psychosis) of the UPDRS
- History of neurological or psychological disorders
- Self-reported signs of depression
- Self-reported swallowing problems
- Stuttering or other speech and language problems
- Non removable metal on, in or close to the head (e.g., piercings, dental braces, medical devices such as deep brain stimulation electrodes)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study endpoints parameters are:<br /><br><br /><br>- Displacement of the tongue tip, the tongue body, the lips and the jaw at<br /><br>consonant and vowel targets.<br /><br>- Velocity of tongue of the tongue tip, the tongue body, the lips and the jaw<br /><br>at key landmarks of speech gestures.<br /><br>- Duration of speech gestures produced with of the tongue tip, the tongue body,<br /><br>the lips and the jaw.<br /><br>- Speech rate (syllables/min and words/min).</p><br>
- Secondary Outcome Measures
Name Time Method <p>The secundary study endpoints parameters are:<br /><br>- F1 and F2 formant measures during the production of vowels (acoustic)<br /><br>- Intensity of the speech signal during the production of stops (acoustic)</p><br>