The essential role of speech motor regions in processing variation in speech: a Transcranial Magnetic Stimulation study
- Conditions
- niet van toepassingnvt.
- Registration Number
- NL-OMON32812
- Lead Sponsor
- F.C. Donders Centre for Cognitive Neuroimaging
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 38
Inclusion Criteria
Right-handed
Native speakers of Dutch
Exclusion Criteria
Epilepsy
Metal in the body
Pacemaker
Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The effect of TMS on the three stimulation sites in the main experiment will be<br /><br>assessed using a behavioural task, i.e., a response time (RT) task in which the<br /><br>difference in RT and the proportion of correct responses are the dependent<br /><br>variables. In one condition, listeners hear sentences in a familiar accent, and<br /><br>in a second condition they hear sentences in an unfamiliar regional accent. The<br /><br>main study parameter is the difference in RT across conditions before and after<br /><br>TMS. The proportion of errors is the secondary parameter. It is predicted that<br /><br>RTs are slower for the unfamiliar regional accent and an interaction is<br /><br>expected between condition and pre-and post stimulation to left vPMC, resulting<br /><br>in a further slowing down of RTs for the unfamiliar accent after stimulation. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary parameter are the motor evoked potentials (MEPs), which are<br /><br>measured every 3 minutes immediately after the two types of stimulation in the<br /><br>pilot experiment for 30 minutes. This results in 10 measurements for each<br /><br>cortical site per participant.</p><br>