High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation

Not Applicable

Completed

• Conditions: Decompression Sickness; SCUBA Diving
• Interventions: Other: High intensity exercise

• Registration Number: NCT02064361
• Lead Sponsor: University Hospital of Split

Brief Summary

The purpose of this study is to determine the impact of high intensity,anaerobic exercise, in the form of cycling, on SCUBA diving. Outcomes are determined by the quantification and subtype of circulating microparticles, complete blood counts, and the quantification of venous gas emboli, measured via transthoracic echocardiography, in the cardiac cavities.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02
• Primary Completion: 2013-05
• Study Completion: 2013-05
• Status Verified: 2014-02
• Study First Submitted: 2014-02-12
• Study First Submitted QC: 2014-02-13
• Last Update Submitted: 2014-02-13
• Study First Posted: 2014-02-17
• Last Update Posted: 2014-02-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

• Experienced divers (> 250 logged dives)
• Male
• Physician clearance to dive

Exclusion Criteria

• Prior incidence of decompression sickness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
High intensity exercise	High intensity exercise	A dive to 18 meters sea water for a duration of 41 minutes preceded by high intensity cycling

Primary Outcome Measures

Name	Time	Method
Change from baseline values of number of circulating microparticles per microliter of blood	Prior to exercise, prior to diving, 15 and 120 minutes after surfacing

Trial Locations

Locations (2)

University of Split School of Medicine; 🇭🇷 Split, Dalmatia, Croatia

University of Maryland; 🇺🇸 Baltimore, Maryland, United States