The effect of vitamin E on nephropathy complications of diabetic patients

Phase 3

• Conditions: diabetic nephropathy.; non-insulin-dependent diabetic melitus with renal complications; E11.2

• Registration Number: IRCT2014122020374N1
• Lead Sponsor: Kashan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patient with diabetic nephropathy
Aged 40 to 85 years
Proteinuria level > 0.3 g/24 h with or without circulating levels of serum creatinine.

Exclusion Criteria

The consumption of vitamin E supplements within 3 months
Patients with uncontrolled diabetes,
Pregnant women
Those with liver or inflammatory diseases

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tumour necrosis factor-alpha (TNF-alpha). Timepoint: Before and three months after intervention. Method of measurement: In serum sample will assessed.by an enzyme-linking immunosorbent assay (ELISA) kit. pg/ml.;Matrix metalloproteinases 9(MMP9). Timepoint: Before and three months after intervention. Method of measurement: In serum sample will assessed by ELISA kit. ng/ml.;Matix metalloproteinas 2(MMP2). Timepoint: Before and three months after intervention. Method of measurement: In serum sample will assessed .by ELISA kit. ng/ml.