Efficacy verification of a halitosis-preventive mouthwash on oral malodorous reductio
- Conditions
- Healthy male/female adults
- Registration Number
- JPRN-UMIN000044864
- Lead Sponsor
- CPCC Company Limited
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 20
Not provided
(1) Subjects who are continuously taking medicines that may affect the test results, except applying a nasal spray and eye drops. (2) Subjects who have any spots with not less than 7 mm of probing pocket depth. (3) Subjects who are undergoing dental treatment for tooth decay, gingivitis, etc., or ones having tooth decay. (4) Subjects equipped with partial/full dentures. (5) Subjects being in the process of straightening their teeth. (6) Subjects who have any tooth defecting, or coming off. (7) Subjects having a severe medical history of dry mouth symptom, Sjogren's syndrome, or systemic illness. (8) Subjects who have previous and/or current medical history of serious diseases (e.g., heart, liver, kidney, digestive organ). (9) Females who are pregnant, lactating, or possibly pregnant. (10) Subjects who are taking medicine, foods with functional claims, health foods, and oral care products (mouthwash, etc.) that may affect the improvement of oral function. (11) Subjects with an extremely irregular dietary habits or lifestyle (e.g. alternative work schedule, graveyard shift). (12) Subjects who take excessive alcohol. (13) Subjects who are allergic to drugs or foods. (14) Subjects who are participating or have been participated to the other clinical tests with some kind of medicine/food within the last 4 weeks before this trial, or planning to join those after giving informed consent. (15) Others who have been determined as ineligible for participation, according to the principal/sub investigator's opinion.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Concentration of hydrogen sulfide
- Secondary Outcome Measures
Name Time Method 1. The number of bacteria in saliva 2. Autoinducer-2 activity 3. Concentration of methyl mercaptan 4. Concentration of dimethyl sulfide