An observational study of outcomes in adult lupus nephritis patients : a nationwide retrospective cohort study.
Not Applicable
- Conditions
- upus nephritis
- Registration Number
- JPRN-UMIN000024090
- Lead Sponsor
- Japanese Society of Nephrology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 600
Inclusion Criteria
Not provided
Exclusion Criteria
1)No medical records at 6 months or later after renal biopsy. Patients who reached a 50% increase in serum creatinine, end stage renal failure requiring renal replacement therapy or died were not excluded. 2)Insufficient biopsy sample for the diagnosis of ISN/RPS classification 3)Patients who are judged to be inappropriate for the study by the investigator. 4)Patients who decline participation of the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Doubling of serum creatinine or end-stage renal disease requiring renal replacement therapy
- Secondary Outcome Measures
Name Time Method 1) A 50% increase in serum creatinine 2) End-stage renal disease requiring renal replacement therapy 3) Good renal outcome (serum creatinine =< 1.0mg/dl, at the final observation) 4) Death 5) Cardiovascular diseases 6) Malignant tumor 7) Complete remission at 6 months after initiation of treatment (or renal biopsy) 8) Complete remission at 12 months after initiation of treatment (or renal biopsy) 9) Repeat biopsy