nraveling Incomplete Lupus - search for prognostic factors for progression to Systemic Lupus Erythematosus
Recruiting
- Conditions
- lupusSLE10003816
- Registration Number
- NL-OMON45013
- Lead Sponsor
- niversitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 143
Inclusion Criteria
Incomplete Lupus patients:
- ANA positivity with a titre of at least 1:80 or higher
- Two other ACR criteria of SLE
- Disease duration of < 5 years
- (Preferable) not yet treated with hydroxychloroquine or corticosteroids
- Being able to give informed consent
Exclusion Criteria
- Concomitant chronic diseases that may affect immune system (such as prior or current malignant disease, active infectious disease, other rheumatological disease, kidney disease, active allergy etc.)
- Pregnancy
- < 18 years old
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main parameter is expression of IFN type I signature</p><br>
- Secondary Outcome Measures
Name Time Method