PRediction Of Flares In Lupus with autoantibodiEs and chemokines (PROFILE)
Completed
- Conditions
- lupusSLE10003816
- Registration Number
- NL-OMON51008
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
In order to be eligible to participate in this study, a subject must meet all
of the following criteria:
• Have a diagnosis of SLE according to EULAR/ACR criteria
• Age >= 18 years
Exclusion Criteria
• Subjects participating in another study in which the subject receives
immunosuppressant medication
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- Profile of autoantibodies and chemokines in visits previous to recorded<br /><br>flares, compared to visits previous to no recorded flares.<br /><br>- Changes in the profile of autoantibodies and chemokines in patients with<br /><br>lower reported quality of life measured by LupusQoL questionnaire, compared to<br /><br>previous visits of the same patient.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Changes in titer levels of autoantibodies before and after start of biological<br /><br>treatment.</p><br>