RE-COVERY DVT/PE: Global Study on Treatment Secondary Prevention of Acute Venous Thromboembolism
- Conditions
- Venous Thromboembolism
- Registration Number
- NCT02596230
- Lead Sponsor
- Boehringer Ingelheim
- Brief Summary
RE-COVERY is a large, multi-national, multi-center observational study based on new data collection. The study will enroll and characterize patients within 30 days of being diagnosed with an acute DVT and/or PE. The study has two main objectives. Objective 1 will characterize the DVT / PE patient population. All patients with a DVT and/or PE will be enrolled for cross-sectional characterization of the VTE patient population. Objective 2 will compare the safety and effectiveness of dabigatran etexilate regimens for treatment of VTE in comparison to VKA regimens. Patients treated with dabigatran etexilate or VKA will be followed up for the occurrence of outcome events for up to one year.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 7797
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Objective 1: Anticoagulant Treatment Baseline collected within 14 days but not more than 6 months after diagnosis of acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Type of treatment received following acute Venous Thromboembolism (VTE) event of eligible patients collected for Objective 1 during baseline at the time of index event. Aim of Objective 1 was to characterize the Venous Thromboembolism (VTE) patient population including the initial acute event phase, i.e. all patients regardless of treatment. Patients who enrolled in Objective 1 and were treated with VKA or dabigatran were also eligible for Objective 2. The aim of objective 2 was to analyze the safety and effectiveness of dabigatran regimens in the treatment of DVT and PE over 1 year of follow-up in comparison to a VKA regimen.
The arm presented in this endpoint was separated into three arms in the participant flow tables ("Not assigned to Dabigatran etexilate or Vitamin K antagonist","Dabigatran etexilate (1)" and "Vitamin K antagonist (1)") in order to distinguish patients participating in both objectives from patients only in objective 2.Objective 2: Incidence Rate of ISTH (International Society on Thrombosis and Haemostasis) Major Bleeding and CRNMB (Clinically Relevant Non Major Bleeding) Per 100 Patient-years (Pt-yrs) 12 months following acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Incidence rate of ISTH (International Society on Thrombosis and Haemostasis) major bleeding and CRNMB (clinically relevant non major bleeding) per 100 patient-years (1/(100\*patient-years)). Each patient in the two treatment groups was weighted proportionally to the probability of that patient being assigned to the opposite treatment group, conditional on relevant observed baseline variables. The propensity scores were estimated using the multivariable logistic regression model.
For the restricted patient set, as a sensitivity analysis, the calculation of incidence rates and cumulative risks was performed without censoring at permanent discontinuation.Objective 2: Symptomatic Recurrent VTE (Venous Thromboembolism) Including VTE Related Mortality 12 months following acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Incidence rate of Symptomatic Recurrent VTE (Venous Thromboembolism) including VTE related mortality per 100 patient-years (1/(100\*patient-years)). Each patient in the two treatment groups was weighted proportionally to the probability of that patient being assigned to the opposite treatment group, conditional on relevant observed baseline variables. The propensity scores were estimated using the multivariable logistic regression model.
For the restricted patient set, as a sensitivity analysis, the calculation of incidence rates and cumulative risks was performed without censoring at permanent discontinuation.Objective 1: Sex Baseline collected within 14 days but not more than 6 months after diagnosis of acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Sex of eligible patients collected for Objective 1 during baseline at the time of index event. Aim of Objective 1 was to characterize the Venous Thromboembolism (VTE) patient population including the initial acute event phase, i.e. all patients regardless of treatment. Patients who enrolled in Objective 1 and were treated with VKA or dabigatran were also eligible for Objective 2. The aim of objective 2 was to analyze the safety and effectiveness of dabigatran regimens in the treatment of DVT and PE over 1 year of follow-up in comparison to a VKA regimen.
The arm presented in this endpoint was separated into three arms in the participant flow tables ("Not assigned to Dabigatran etexilate or Vitamin K antagonist","Dabigatran etexilate (1)" and "Vitamin K antagonist (1)") in order to distinguish patients participating in both objectives from patients only in objective 2.Objective 1: Index Event Baseline collected within 14 days but not more than 6 months after diagnosis of acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Type of index event (e.g., DVT or PE or DVT and PE) diagnosed at the time of acute Venous Thromboembolism (VTE) event of eligible patients collected for Objective 1 during baseline at the time of index event. Aim of Objective 1 was to characterize the Venous Thromboembolism (VTE) patient population including the initial acute event phase, i.e. all patients regardless of treatment. Patients who enrolled in Objective 1 and were treated with VKA or dabigatran were also eligible for Objective 2. The aim of objective 2 was to analyze the safety and effectiveness of dabigatran regimens in the treatment of DVT and PE over 1 year of follow-up in comparison to a VKA regimen.
The arm presented in this endpoint was separated into three arms in the participant flow tables ("Not assigned to Dabigatran etexilate or Vitamin K antagonist","Dabigatran etexilate (1)" and "Vitamin K antagonist (1)") in order to distinguish patients participating in both objectives from patients only in objective 2.Objective 1: Age Baseline collected within 14 days but not more than 6 months after diagnosis of acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Age in years of eligible patients collected for Objective 1 during baseline at the time of index event. Aim of Objective 1 was to characterize the Venous Thromboembolism (VTE) patient population including the initial acute event phase, i.e. all patients regardless of treatment. Patients who enrolled in Objective 1 and were treated with VKA or dabigatran were also eligible for Objective 2. The aim of objective 2 was to analyze the safety and effectiveness of dabigatran regimens in the treatment of DVT and PE over 1 year of follow-up in comparison to a VKA regimen.
The arm presented in this endpoint was separated into three arms in the participant flow tables ("Not assigned to Dabigatran etexilate or Vitamin K antagonist","Dabigatran etexilate (1)" and "Vitamin K antagonist (1)") in order to distinguish patients participating in both objectives from patients only in objective 2.
- Secondary Outcome Measures
Name Time Method Objective 2: Incidence Rate of Recurrent DVT and/or PE 12 months following acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Incidence rate of Recurrent Deep Vein Thrombosis (DVT) and/or Pulmonary Embolism (PE) per 100 patient-years (1/(100\*patient-years)). Each patient in the two treatment groups was weighted proportionally to the probability of that patient being assigned to the opposite treatment group, conditional on relevant observed baseline variables. The propensity scores were estimated using the multivariable logistic regression model.
For the restricted patient set, as a sensitivity analysis, the calculation of incidence rates and cumulative risks was performed without censoring at permanent discontinuation.Objective 2: Incidence Rate of VTE-related Mortality 12 months following acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Incidence rate of VTE-related Mortality per 100 patient-years (1/(100\*patient-years)). Each patient in the two treatment groups was weighted proportionally to the probability of that patient being assigned to the opposite treatment group, conditional on relevant observed baseline variables. The propensity scores were estimated using the multivariable logistic regression model.
For the restricted patient set, as a sensitivity analysis, the calculation of incidence rates and cumulative risks was performed without censoring at permanent discontinuation.Objective 2: Incidence Rate of All-cause Mortality 12 months following acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Incidence rate of all-cause mortality per 100 patient-years (1/(100\*patient-years)). Each patient in the two treatment groups was weighted proportionally to the probability of that patient being assigned to the opposite treatment group, conditional on relevant observed baseline variables. The propensity scores were estimated using the multivariable logistic regression model.
For the restricted patient set, as a sensitivity analysis, the calculation of incidence rates and cumulative risks was performed without censoring at permanent discontinuation.
Trial Locations
- Locations (222)
University General Hospital of Thessaloniki AHEPA
🇬🇷Thessaloniki, Greece
Dr. Kenessey Albert Kórház-Rendelõintézet, Balassagyarmat
ðŸ‡ðŸ‡ºBalassagyarmat, Hungary
Johns Hopkins University
🇺🇸Baltimore, Maryland, United States
University Of Mississippi Medical Center
🇺🇸Jackson, Mississippi, United States
Hospital Italiano
🇦🇷Caba, Argentina
ICBA
🇦🇷Caba, Argentina
Clinica Juncal
🇦🇷Temperley, Argentina
LKH-Univ. Hospital Graz
🇦🇹Graz, Austria
C.H.U. de Charleroi
🇧🇪Charleroi, Belgium
UMHAT St. George
🇧🇬Plovdiv, Bulgaria
Hospital Trakia Park
🇧🇬Stara Zagora, Bulgaria
Centro de Investigaciones Clinicas S.A.S
🇨🇴Cali, Colombia
Promotora Medica Las Americas SA
🇨🇴Medellin, Colombia
General Hospital of Athens "G. Gennimatas"
🇬🇷Thessaloniki, Greece
Jasz-Nagykun-Szolnok Megyei Hetenyi G. Korhaz-Rendelointezet
ðŸ‡ðŸ‡ºSzolnok, Hungary
Rafik Hariri University Hospital
🇱🇧Beirut, Lebanon
OLVG, locatie Oosterpark
🇳🇱Amsterdam, Netherlands
Tweesteden Ziekenhuis, locatie Tilburg
🇳🇱Tilburg, Netherlands
The University Of Texas at Houston
🇺🇸Houston, Texas, United States
Health and Life Research Institute, LLC
🇺🇸Miami, Florida, United States
Cardiovascular Innovation and Research Center
🇺🇸Long Beach, California, United States
Med-Care Research
🇺🇸Miami, Florida, United States
Wellstar Cardiovascular Medicine
🇺🇸Marietta, Georgia, United States
Tampa General Hospital
🇺🇸Tampa, Florida, United States
Pines Care Research Center
🇺🇸Pembroke Pines, Florida, United States
Genesys Regional Medical Center
🇺🇸Grand Blanc, Michigan, United States
Ellipsis Group
🇺🇸Atlanta, Georgia, United States
Fox Valley Clinical Research Center, LLC
🇺🇸Aurora, Illinois, United States
Hospital Universitario Austral
🇦🇷Buenos Aires, Argentina
Cardiology Center of Houston, PA
🇺🇸Katy, Texas, United States
Vseobecna fakultni nemocnice V Praze
🇨🇿Praha 2, Czechia
Institute for Clinical and Experimental Medicine
🇨🇿Praha 4, Czechia
Diagangio s.r.o.
🇨🇿Brno, Czechia
Sanford Cardiology
🇺🇸Sanford, North Carolina, United States
Hospital Vera Cruz
🇧🇷Belo Horizonte, Brazil
Lycoming Internal Medicine, Inc
🇺🇸Jersey Shore, Pennsylvania, United States
Vidant Multispecialty Clnc Kinston
🇺🇸Kinston, North Carolina, United States
Research Associates of Jackson
🇺🇸Jackson, Tennessee, United States
Cardio Voyage
🇺🇸McKinney, Texas, United States
Juravinski Hospital - Hamilton Health Sciences
🇨🇦Hamilton, Ontario, Canada
Waukesha Heart Institute
🇺🇸Waukesha, Wisconsin, United States
Rehabilitacni nemocnice Beroun
🇨🇿Beroun, Czechia
University Hospital Brno
🇨🇿Brno, Czechia
Hospital das Clinicas da Faculdade de Medicina - FMUSP
🇧🇷São Paulo, Brazil
H.-Hartziekenhuis
🇧🇪Lier, Belgium
Fakultni nemocnice u sv. Anny v Brne
🇨🇿Brno, Czechia
Hamilton General Hospital
🇨🇦Hamilton, Ontario, Canada
MUDr. Stanislav Bulir
🇨🇿Mlada Boleslav, Czechia
Nemocnice Náchod
🇨🇿Nachod, Czechia
Fakultni nemocnice Plzen
🇨🇿Plzen, Czechia
Centro de Diagnostico Cardilogico
🇨🇴Cartagena, Colombia
Universitätsklinikum Heidelberg
🇩🇪Heidelberg, Germany
Städtisches Klinikum Dresden
🇩🇪Dresden, Germany
Nemocnice Milosrdnych bratri
🇨🇿Brno, Czechia
MUDr. Ladislav Busak
🇨🇿Louny, Czechia
Dr. Ashraf ElGhandour Private Clinic
🇪🇬Alexandria, Egypt
CTC Hodonin s.r.o.
🇨🇿Hodonin, Czechia
Universitätsmedizin Greifswald
🇩🇪Greifswald, Germany
Private Clinic - Dr. Shawky
🇪🇬Cairo, Egypt
St. Istvan Hospital, Budapest
ðŸ‡ðŸ‡ºBudapest, Hungary
Gen. Hosp. of Chest Diseases "Sotiria", 3rd Internal Med. Cl
🇬🇷Athens, Greece
Franziskus-Krankenhaus, Berlin
🇩🇪Berlin, Germany
Jahn Ferenc Del-Pest Hospital
ðŸ‡ðŸ‡ºBudapest, Hungary
University Debrecen Hospital
ðŸ‡ðŸ‡ºDebrecen, Hungary
Csongrad Country Dr Bugyi Istvan Hosp.
ðŸ‡ðŸ‡ºSzentes, Hungary
Osp. Civico e Benfratelli "M. Ascoli e G. Di Cristina"
🇮🇹Palermo, Italy
Dorottya Kanizsai Hospital
ðŸ‡ðŸ‡ºNagykanizsa, Hungary
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of
Inje University Busan Paik Hospital
🇰🇷Busan, Korea, Republic of
Clinica Villa dei Fiori
🇮🇹Acerra, Italy
Ospedale Civile degli Infermi
🇮🇹Faenza (RA), Italy
Pest Megyei Flor Ferenc Hospital
ðŸ‡ðŸ‡ºKistarcsa, Hungary
Azienda Ospedaliera Vito Fazzi
🇮🇹Lecce, Italy
Dong-A University Hospital
🇰🇷Busan, Korea, Republic of
Hallym University Sacred Heart Hospital
🇰🇷Anyang-si, Korea, Republic of
Ospedali Riuniti di Ancona
🇮🇹Macerata, Italy
Keimyung University Dongsan Medical Center
🇰🇷Daegu, Korea, Republic of
Soonchunhyang University Hospital Seoul
🇰🇷Seoul, Korea, Republic of
Riga East University Hospital
🇱🇻Riga, Latvia
Ain Wazein Hospital
🇱🇧El-Chouf, Lebanon
Centre Hospitalier Universitaire Notre Dame de Secours
🇱🇧Jbeil, Lebanon
Amphia Ziekenhuis
🇳🇱Breda, Netherlands
Szpital Uniwersytecki nr 2 im.dr J. Biziela
🇵🇱Bydgoszcz, Poland
4. Military Clinical Hospital with Polyclinic SP ZOZ
🇵🇱Wroclaw, Poland
Centro Hospitalar Universitário do Porto, EPE - Hospital de Santo António
🇵🇹Porto, Portugal
Hospital CUF Porto
🇵🇹Porto, Portugal
Medical Center "Angioline"
🇷🇺Ekaterinburg, Russian Federation
Centro Hospitalar de Vila Nova de Gaia
🇵🇹Vila Nova de Gaia, Portugal
Clinical hospital of BGMU
🇷🇺Ufa, Russian Federation
Clinical emergency hospital #15
🇷🇺Volgograd, Russian Federation
Institute for Cardiovascular diseases Dedinje
🇷🇸Belgrade, Serbia
General Hospital MediGroup
🇷🇸Belgrade, Serbia
Yaroslavl Regional Clin. Hospital
🇷🇺Yaroslavl, Russian Federation
King Fahad Medical City
🇸🇦Riyadh, Saudi Arabia
Barnsley Hospital
🇬🇧Barnsley, United Kingdom
Karaman Government Hospital
🇹🇷Karaman, Turkey
RTE University Medical Faculty
🇹🇷Rize, Turkey
Gia Dinh People Hospital
🇻🇳Ho Chi Minh, Vietnam
Queen's Hospital
🇬🇧Burton on Trent, United Kingdom
University Hospital of North Durham
🇬🇧Durham, United Kingdom
Birmingham Heartlands Hospital
🇬🇧Birmingham, United Kingdom
North Tyneside General Hospital
🇬🇧North Shields, United Kingdom
Ospedale san Lazzaro
🇮🇹Alba, Italy
Policlinico di Bari
🇮🇹Bari, Italy
P.O. di Castelfranco Veneto
🇮🇹Castelfranco Veneto, Italy
Spedali Riuniti di Livorno
🇮🇹Livorno, Italy
SUN Seconda Università Napoli
🇮🇹Napoli, Italy
Ospedale Gaetano Bernabeo
🇮🇹Ortona (CH), Italy
Azienda Universitaria-Universita' La Sapienza
🇮🇹Roma, Italy
Univ. Cattolica del Sacro Cuore
🇮🇹Roma, Italy
A. O. Ospedale Circolo Fond. Macchi
🇮🇹Varese, Italy
A. O. Ospedale di Vimercate
🇮🇹Vimercate (Mi), Italy
Bakirköy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi Zuhura
🇹🇷Istanbul, Turkey
Faculdade de Ciencias Medicas da UNICAMP
🇧🇷Campinas, Brazil
Severance Hospital
🇰🇷Seoul, Korea, Republic of
Daegu Catholic University Medical Center
🇰🇷Daegu, Korea, Republic of
Praxis für Gefäßmedizin
🇩🇪Goerlitz, Germany
Kyung Hee University Hospital at Gangdong
🇰🇷Seoul, Korea, Republic of
St. Luke's Medical Center, QC
🇵ðŸ‡Quezon City, Philippines
Emergency University Hospital, Bucharest
🇷🇴Bucharest, Romania
MUDr. Dalibor Musil
🇨🇿Olomouc, Czechia
University General Hospital Attikon
🇬🇷Athens, Greece
Univ. Gen. Hosp. of Ioannina
🇬🇷Ioannina, Greece
Ospedale Civile
🇮🇹Sassari, Italy
The Catholic University of Korea, Seoul St.Mary's Hospital
🇰🇷Seoul, Korea, Republic of
Bellevue Medical Center
🇱🇧Beirut, Lebanon
Philippine General Hospital
🇵ðŸ‡Manila, Philippines, Philippines
Palmerston North Hospital
🇳🇿Palmerston North, New Zealand
St. Antonius ziekenhuis, locatie Nieuwegein
🇳🇱Nieuwegein, Netherlands
Clinical Center Kragujevac
🇷🇸Kragujevac, Serbia
Clinical Medical Center Zvezdara, Belgrade
🇷🇸Belgrade, Serbia
General Hospital Valjevo
🇷🇸Valjevo, Serbia
ALIAN s.r.o., Bardejov, Dzupinova, Maria
🇸🇰Bardejov, Slovakia
MEDIVASA s.r.o., Outpatient Clinic, Zilina
🇸🇰Zilina, Slovakia
KARDIO-ANGIO, s.r.o.
🇸🇰Levice, Slovakia
HeMart, s.r.o.
🇸🇰Martin, Slovakia
Phramongkutklao Hospital
🇹ðŸ‡Bangkok, Thailand
Ramathibodi Hospital
🇹ðŸ‡Bangkok, Thailand
UCC Maribor
🇸🇮Maribor, Slovenia
GH Celje
🇸🇮Celje, Slovenia
ABE-AS, s.r.o.
🇸🇰Nitra, Slovakia
Univ. Clinic of Respiratory and Allergic Diseases, Golnik
🇸🇮Golnik, Slovenia
Hospital Topolsica
🇸🇮Topolsica, Slovenia
Gazi University Medical Faculty
🇹🇷Ankara, Turkey
Uludag University Medical Faculty
🇹🇷Bursa, Turkey
Thammasat University Hospital
🇹ðŸ‡Pathum Tani, Thailand
Suleyman Demirel University Medical Faculty
🇹🇷Isparta, Turkey
Medipol University Medical Faculty
🇹🇷Istanbul, Turkey
Ankara Atatürk Training and Research Hospital
🇹🇷Ankara, Turkey
Dicle University Medical Faculty
🇹🇷Diyarbakir, Turkey
Dr. Ersin Arslan Public Hospital
🇹🇷Gaziantep, Turkey
Izmir Tepecik Training and Research Hospital
🇹🇷Izmir, Turkey
Ege University Medical Faculty
🇹🇷Izmir, Turkey
Kayseri Training And Research Hospital
🇹🇷Kayseri, Turkey
Ozel Uzmanlar Yalova Hospital
🇹🇷Yalova, Turkey
Thumbay Hospital
🇦🇪Dubai, United Arab Emirates
North Hampshire Hospital
🇬🇧Basingstoke, United Kingdom
Craigavon Area Hospital
🇬🇧Portadown, United Kingdom
Wythenshawe Hospital
🇬🇧Manchester, United Kingdom
Bach Mai hospital
🇻🇳Hanoi, Vietnam
Salisbury District Hospital
🇬🇧Salisbury, United Kingdom
Cho Ray Hospital
🇻🇳Ho Chi Minh, Vietnam
115 People Hospital
🇻🇳Ho Chi Minh, Vietnam
University Medical Center of Ho Chi Minh City
🇻🇳Ho Chi Minh city, Vietnam
Private Clinic - Dr. Ahmed Hassouna
🇪🇬Kalyoub, Egypt
Daugavpils Regional Hospital
🇱🇻Daugavpils, Latvia
Hammoud Hospital University Medical Center
🇱🇧Saida, Lebanon
Instituto Jalisciense de Metabolismo, SC
🇲🇽Guadalajara, Mexico
Hospital Ponta Delgada
🇵🇹Ponta Delgada, Portugal
Novosibirsk Research Institute
🇷🇺Novosibirsk, Russian Federation
City Clinical Hospital No. 2, St. Petersburg
🇷🇺St. Petersburg, Russian Federation
Dorozghnaya hospital
🇷🇺St.Petersburg, Russian Federation
Clinical Centre Nis
🇷🇸Nis, Serbia
Hospital #15 named after O.M.Filatov
🇷🇺Moscow, Russian Federation
City Clinical Hospital 1 (1-Gradskaya)
🇷🇺Moscow, Russian Federation
LKH Feldkirch
🇦🇹Feldkirch, Austria
MHAT 'Tokuda Hospital Sofia', EAD
🇧🇬Sofia, Bulgaria
Fundacion Cardiomet CEQUIN
🇨🇴Armenia, Colombia
Asociacion IPS Medicos Internistas de Caldas
🇨🇴Manizales, Colombia
"Laiko" Hospital, 1st Vascular Surgery Clinic of UOA
🇬🇷Athens, Greece
General University Hospital of Larissa
🇬🇷Larissa, Greece
Private Clinic Dr. Mervat Mattar
🇪🇬Cairo, Egypt
Hospital Aleman
🇦🇷Caba, Argentina
Medical University of Innsbruck
🇦🇹Innsbruck, Austria
ULB Hopital Erasme
🇧🇪Bruxelles, Belgium
National Heart Hospital, Sofia
🇧🇬Sofia, Bulgaria
SMOLAM
🇨🇱Santiago, Chile
Athens Hospital of Chest Diseases "Sotiria"
🇬🇷Athens, Greece
VSV Centrs, Stalte Private Practice, Talsi
🇱🇻Talsi, Latvia
Private Clinic Mohamed Moussa
🇪🇬Cairo, Egypt
Centre Hospitalier Universitaire de Liège
🇧🇪Liège, Belgium
Unidad de Investigaciones ClÃnicas
🇨🇴Cali, Colombia
University Hospital of Alexandroupolis
🇬🇷Alexandroupolis, Greece
Pecsi Tudomanyegyetem
ðŸ‡ðŸ‡ºPecs, Hungary
Hospital Raja Perempuan Zainab II, Kota Bharu
🇲🇾Kota Bahru, Malaysia
Hospital_Angeles Centro Médicodel PotosÃ
🇲🇽San Luis PotosÃ, Mexico
Arke Estudios Clinicos SA de CV
🇲🇽Veracruz, Mexico
Makati Medical Center
🇵ðŸ‡Makati, Philippines
Mazowiecki Szpital Specjalistyczny im. dr Jozefa Psarskiego
🇵🇱Ostroleka, Poland
Private Practice Cardiology Dr. Pop Calin Florin
🇷🇴Baia Mare, Romania
Rostov Medical University
🇷🇺Rostov on Don, Russian Federation
Liepaja Regional Hospital, Therapy Department
🇱🇻Liepaja, Latvia
Gita Rancane Doctor Practice in Cardiology
🇱🇻Ventspils, Latvia
Clemenceau Medical Center
🇱🇧Beirut, Lebanon
SPZOZ Wojewodzki Szpital Specjalistyczny nr 4
🇵🇱Bytom, Poland
Spitalul Clinic Municipal Cluj Napoca
🇷🇴Cluj-Napoca, Romania
LLC Medical Union New Hospital
🇷🇺Ekaterinburg, Russian Federation
City Hospital Saint Elizaveta, Dept. Endocrinology
🇷🇺St. Petersburg, Russian Federation
Clinical Center Bezanijska kosa, Belgrade
🇷🇸Belgrade, Serbia
Inst. for Pulm. Diseases of Vojvodine, Clinic f. Pulm. Oncol
🇷🇸Sremska Kamenica, Serbia
City Clinical Hospital n.a. V.V. Veresaev
🇷🇺Moscow, Russian Federation
American University of Beirut Medical Center
🇱🇧Beirut, Lebanon
University Malaya Medical Centre
🇲🇾Kuala Lumpur, Malaysia
Clinica Vascular de Guadalajara
🇲🇽Guadalajara, Mexico
Centro Medico Piura
🇵🇪Piura, Peru
State Autonomous Institution of Health
🇷🇺Kemerovo, Russian Federation
St.Petersburg State Medical University n. a. II Mechnikov
🇷🇺St.Petersburg, Russian Federation
Voronezh Regional Hospital N1
🇷🇺Voronezh, Russian Federation
Clinical Center of Serbia
🇷🇸Belgrade, Serbia
Regional Clinical Hospital#3
🇷🇺Chelyabinsk, Russian Federation
Federal Research and Clinical Center of Special Medical Help
🇷🇺Moscow, Russian Federation
St Thomas' Hospital
🇬🇧London, United Kingdom