Study of the effect of N-acetyl cysteine on the renal graft function biomarkers (IL18, NGAL)
Phase 2
- Conditions
- Delayed graft function after kidney transplantation.Other disorders of kidney and ureter in other diseases classified elsewhereN29.8*
- Registration Number
- IRCT201109067490N1
- Lead Sponsor
- Department of Nephrology, Shahid Labbafinejad Medical Center and Urology and Nephrology Research Cen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Inclusion Criteria: patient receiving transplantation from living donors.
Exclusion Criteria
having a neoplastic disease; brain tumor; having inflammatory diseases in their active phase (SLE); an acute infection, meningitis, sepsis; Sickle Cell Disease; Pregnancy; Cardio-renal syndrome; endogenous Cushing's syndrome; chronic use of cimetidine; a history of acute pancreatitis in recent months; Multiple Sclerosis; cardiac bypass in a recent month; cirrhosis due to Hepatitis C; having Alzheimer's disease; having a untreated major depressive illness or schizophrenia; Stroke in recent months; Hyperoxaluria sensitivity to sulfonamides.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IL 18, NGAL. Timepoint: 4 and 24 hr after transplantation. Method of measurement: Elisa kit.
- Secondary Outcome Measures
Name Time Method Dialysis requirement. Timepoint: 60 days after transplantation. Method of measurement: observation.