Comparison of Multiple Oxygenation Targets With Different Oximeters in COPD and Non-COPD Patients- Impact on Oxygen Flows
Overview
- Phase
- Not Applicable
- Intervention
- Nellcor oximeter
- Conditions
- COPD Exacerbation
- Sponsor
- Laval University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Oxygen flow
- Status
- Completed
- Last Updated
- last month
Overview
Brief Summary
The oximeter is an instrument for monitoring patients receiving oxygen therapy. It displays pulse oxygen saturation (SpO2), which is a reflection of arterial oxygen saturation (SaO2). An accurate SpO2 value is essential for optimal management of the O2 flow delivered to patients. Several factors can influence this measurement and the choice of ventilatory support: the type of oximeter used, skin pigmentation and the oxygenation goal.
The objective of our study is to evaluate the impact of the oxygenation goal and the oximeter used on oxygen flows in patients with COPD (or with hypercapnia, or at risk of hypercapnia) and in patients without COPD (in particular pneumonia, pulmonary fibrosis and other pathologies) Our hypothesis is that the SpO2 target and oximeter used will have an impact on oxygen flows and that these effects will be synergistic in these different populations.
Investigators
François Lellouche
Principal Investigator
Laval University
Eligibility Criteria
Inclusion Criteria
- •≥ 18 years old
- •On conventional oxygen therapy with SpO2 between 88 and 100% with the usual oximeter and nasal cannula.
- •SpO2 \< 92% in ambient air with the usual oximeter
Exclusion Criteria
- •No availability of the SpO2 signal with the usual oximeter
- •False nails or nail polish
- •Severe anemia documented on the last blood count during the current hospitalization (Hb \< 80g/L)
Arms & Interventions
90% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 90% of SpO2.
Intervention: Nellcor oximeter
90% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 90% of SpO2.
Intervention: Masimo oximeter
90% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 90% of SpO2.
Intervention: Nonin oximeter
88% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 88% of SpO2.
Intervention: Masimo oximeter
88% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 88% of SpO2.
Intervention: Nellcor oximeter
88% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 88% of SpO2.
Intervention: Nonin oximeter
92% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 92% of SpO2.
Intervention: Masimo oximeter
92% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 92% of SpO2.
Intervention: Nellcor oximeter
92% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 92% of SpO2.
Intervention: Nonin oximeter
94% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 94% of SpO2.
Intervention: Masimo oximeter
94% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 94% of SpO2.
Intervention: Nellcor oximeter
94% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 94% of SpO2.
Intervention: Nonin oximeter
96% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 96% of SpO2.
Intervention: Masimo oximeter
96% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 96% of SpO2.
Intervention: Nellcor oximeter
96% SpO2 target
During this periods , oxygen will be administered in manual titration to reach 96% of SpO2.
Intervention: Nonin oximeter
Outcomes
Primary Outcomes
Oxygen flow
Time Frame: assessed up to 10 minutes
the mean oxygen flow to reach the SpO2 target +/- 1% during 2 minutes for each period and each oximeter
Secondary Outcomes
- Partial oxygen weaning(assessed up to 10 minutes - until SpO2 target stability for 2 minutes)
- Complete oxygen weaning(assessed up to 10 minutes - until SpO2 target stability for 2 minutes)
- High oxygen flow(assessed up to 10 minutes - until SpO2 target stability for 2 minutes)
- Oximeter bias comparison(assessed up to 10 minutes - until SpO2 target stability for 2 minutes)