Impact of Non-invasive Brain Stimulation, Associated With Upper Limb Robot-assisted Therapy, on Motor Recuperation

Not Applicable

Completed

• Conditions: Stroke

• Registration Number: NCT02512289
• Lead Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Brief Summary

tDCS (transcranial direct current stimulation) and robot assisted therapy (RAT) will be used in chronic stroke patients to improve a variety of functions with upper limb.

Detailed Description

tDCS and RAT will be used in chronic stroke patients to improve a variety of functions such as motor functions with upper limb.

tDCS will be applied in a placebo-controlled, double-blind, randomised fashion. A session of RAT will be associated with tDCS/placebo. Behavioural data will be collected before and after tDCS, associated with RAT.

Study Timeline

• Study Start: 2014-01-09
• Primary Completion: 2014-01-09
• Study First Submitted: 2014-08-25
• Study First Submitted QC: 2015-07-27
• Study Completion: 2015-07-30
• Study First Posted: 2015-07-30
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-23
• Last Update Posted: 2018-08-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• stroke with at least slight deficit in upper limb

Exclusion Criteria

• epilepsy
• contraindication to tDCS
• presence of metal in the head
• inability to understand/complete behavioural tasks
• chronic intake of alcohol or recreative drugs
• major health condition (e.g. terminal renal failure, instable heart failure etc ...)
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Upper Limb Kinematics	kinematic assessment of the upper limb at Baseline (>6 months after stroke), immediately after intervention (20min of tDCS+RAT)

Secondary Outcome Measures

Name	Time	Method
Box and Block test	Manual dexterity assessment at Baseline (>6 months after stroke), immediately after intervention (20min of tDCS+RAT)
Purdue Pegboard Test	Digital dexterity assessment at Baseline (>6 months after stroke), immediately after intervention (20min of tDCS+RAT)

Trial Locations

Locations (2)

Cliniques Universitaires Saint Luc; 🇧🇪 Brussel, Belgium

CHU Dinant-Godinne UCL; 🇧🇪 Mont Godinne, Belgium