Effect of pregabalin premedication on emergence agitation in pediatric infraumblical abdominal surgery after sevoflurane anesthesia , double blinded, randomized placebo control study.
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Oral pregabalin premedication is effective in Emeregence Agitation after Sevoflurane anesthesia
研究概览
简要总结
Emergence agitation (EA) is a temporary condition that occurs while awaking from general anesthesia.
Sevoflurane is very valuable for induction and continuation of anesthesia in pediatrics, but it is correlated with increased ratio of EA.
Medications used to prevent EA may have unwanted adverse effects such as vomiting and delayed recovery.
Pregabalin belongs to gabapentinoid compounds with anticonvulsant, pain killing, and antianxi-ety activity. The target of this study is to define the influence of pregabalin premedication in pe-
diatrics on EA after sevoflurane anesthesia.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 4.00 Year(s) 至 12.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Age: 4-12years 2 mASA physical status 3 Child undergoing Infraumblical Abdominal surgery.
排除标准
- •1 Patient’s parent’s refusal 2 History of developmental delay or mental retardation,which will make observational pain intensity assessment difficult 3 Anatomical abnormalities 4 Bleeding diathesis 5 Coagulation disorder 6 History of renal,hepatic,cardiac disorder upper or lower infection or any neurological abnormalities 7 Emergency cases 8 Cerebral palsy.
结局指标
主要结局
Oral pregabalin premedication is effective in Emeregence Agitation after Sevoflurane anesthesia
时间窗: Day 0 at baseline
in Infraumblical abdominal surgeries.
时间窗: Day 0 at baseline
次要结局
未报告次要终点
研究者
Dr Himanshi
All India institute of medical sciences , Raipur