Functional Vision Consequences of Rehabilitation for TBI Vision Loss
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 110
- 试验地点
- 2
- 主要终点
- Dynamic Visual Field
研究概览
简要总结
The objective of this study is to test functional vision outcome measures that reflect the loss in everyday life tasks that require vision and that are sensitive to changes after a course of vision rehabilitation in Veterans/participants with TBI.
详细描述
Traumatic brain injury (TBI) can cause vision loss because of diffuse or focal neuronal injury. Vision can be compromised because of local injury to one or both optic nerves, diffuse brain injury, and/or limitation in eye movements because of dysfunction of cranial nerves. These typical injuries may compromise any of the neural pathways that subserve afferent or efferent visual function. Self-reports of vision loss include diplopia, visual field loss, light sensitivity, reading problems and contrast sensitivity (color and luminance) loss. This project will pursue the following aims: 1) Identify the relationship between functional vision loss in everyday vision tasks (reading, visual search, way finding) and the characteristics of potential visual impairment (visual acuity, contrast sensitivity, visual fields, stereoacuity, eye movement disorders) associated with TBI; and 2) Determine the ability of the vision rehabilitation interventions (both monotherapy and combination therapy) to improve functional vision outcome measures that reflect everyday visual tasks. The vision rehabilitation interventions incorporated into this study will be Vision Restoration Therapy, NVT Eye Scanning Therapy, and standard Eccentric Viewing Training. These therapies are rehabilitative interventions prescribed for Veterans in Polytrauma Rehabilitation Centers, Blind Rehabilitation Centers, and advocated for VA Medical Center TBI clinics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 79 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •TBI (any form)
- •Hemianopic Visual Field Loss
- •Stable fixation
- •1.0 logMAR or better Reading Acuity
- •20 words per minute or better reading rate
排除标准
- •Visual Neglect
- •medical conditions that prevent sitting for 30 minutes or following instructions
结局指标
主要结局
Dynamic Visual Field
时间窗: Baseline
次要结局
- Dynamic Visual Field(After Second Therapy (Average Time is 9 months))
- Reading Rate and Accuracy(After Second Therapy (average time is 9 months))
- Reading Rate(After First Therapy / Before Second Therapy (average time is 4.5 months))
- Visual Search Accuracy and Timing(After Second Therapy (average time is 9 months))
