Prediction of ventilatory requirement in patients with severe lung disease by using ultrasound machine

Not yet recruiting

Conditions: Chronic obstructive pulmonary disease with (acute) exacerbation,

Registration Number: CTRI/2024/07/070583

Lead Sponsor: Anaesthesia Department Shri B M Patil Medical college hospital and Research center

Brief Summary: COPD is the third leading cause of death worldwide. In case of respiratory failure, ventilatory support is necessary either in the form of NIV or IMV through endotracheal tube. Early use of NIV in patients with acute COPD is beneficial. The decision to institute IMV should be based on clinical judgement that integrates many clinical variables.

Ultrasonography is a non-invasive tool for quantification of diaphragmatic contractility through Diaphragmatic thickness or Diaphragmatic thickness fraction or diaphragmatic impairment. This makes USG assessment a reasonable tool during management plan.

This is a prospective observational study, which is going to happen over a period of 1 year.

The study sample was calculated using statistical package for the social sciences (version 20).

This study helps in assessing the ability of USG in predicting the requirement of IMV after NIV and also the impact of diaphragmatic impairment during ICU stay, MV days, and 28-day mortality.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 95

Inclusion Criteria

Patients of either sex admitted to the intensive care unit with acute exacerbation of chronic obstructive pulmonary disease.

Exclusion Criteria

1.Contraindications of Non-invasive ventilation (unconscious uncooperative patients,shock,severe hemodynamic instability) 2.Neuromuscular disease 3.Chest wall deformities 4.Diaphragmatic palsy.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The value of Diaphragmatic impairment to predict need for invasive mechanical ventilation after NIV failure	On admission, before starting NIV and after starting NIV

Secondary Outcome Measures

Name	Time	Method
Impact of Diaphragmatic impairment.	1. During Mechanical ventilatory days

Trial Locations

Locations (1): Shri B M Patil Medical College Hospital and Research Centre
🇮🇳
Bijapur, KARNATAKA, India
Shri B M Patil Medical College Hospital and Research Centre
🇮🇳Bijapur, KARNATAKA, India
Dr Kola Samatha Reddy
Principal investigator
9481121645
reddysamathas84@gmail.com