跳至主要内容
临床试验/CTRI/2024/04/066257
CTRI/2024/04/066257尚未招募不适用

Age and Gender Specific Sarcopenia Nomogram for Indian Children

Prof Mohamed Rela1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2024年5月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
1,000
试验地点
1
主要终点
Formulation of age and gender based nomogram for total psoas muscle area for Indian Children

研究概览

简要总结

Current literature strongly recommends sarcopenia and frailty assessment over routine anthropometric measurements to predict outcomes in any chronic illness and its treatment. All the currently available scales are based on western data. Unfortunately, there is no data on the normal range of muscle mass from our population and this skews comparison and outcomes.

In a first of its kind, we intend to develop an age and gender specific nomogram for normal muscle mass in children from the Indian subcontinent. The sum of psoas muscle area at L3-L4 intervertebral disc on CT scan of children who undergo CT for trauma or acute illness across age groups from 1-16 years are collected. We are looking to collect 1000 such scans to make a reliable nomogram. The data will be completely anonymised as only the age, gender and psoas muscle data is required.

This will enable an India-specific nomogram to accurately define frailty and sarcopenia in the pediatric population which will in turn help in predicting and prognosticating the nutritional status of children with any chronic pathology. The trend when charted will also help in assessment of reversal of sarcopenia

研究设计

研究类型
Observational

入排标准

年龄范围
1.00 Year(s) 至 16.00 Year(s)(—)
性别
All

入选标准

  • Calculation of total psoas muscle area (sum of right and left posts muscle area) at L3-4 level intervertebral disc on CT scans done for any acute indication.

排除标准

  • Chronic illnesses like chronic liver and kidney diseases, malignancies, spinal trauma, myopathies and cerebral palsy.

结局指标

主要结局

Formulation of age and gender based nomogram for total psoas muscle area for Indian Children

时间窗: Day-0 of CT scan - single time point

次要结局

  • Sarcopenia comparison of children with chronic disorders with the age and gender based nomogram values and their correlation with outcomes(Day 30, Day 90, day 180, 1 year)

研究者

发起方
Prof Mohamed Rela
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Prof Mohamed Rela

Rela Institute and Medical Centre

研究点 (1)

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