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临床试验/NCT00935571
NCT00935571Unknown不适用

Incidence of Postthoracotomy Pain Following General Anesthesia: A Comparison Between TIVA and Inhalation Anesthesia

Asan Medical Center1 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2007年10月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
入组人数
400
试验地点
1
主要终点
Incidence of pain

研究概览

简要总结

The purpose of this study is to evaluate the incidence of postthoracotomy pain between total intravenous anesthesia (TIVA)and inhalation anesthesia after lung surgery.

详细描述

Thoracotomy is one of the most painful surgical incisions. It has been shown that 5-80% of patients still suffer from thoracic pain 2-3 months after surgery and the international association for the study of pain (IASP) defines postthoracotomy pain syndrome (PTTS)as pain that recurs or persists at least 2 months after surgical procedure. Previous reports have shown that the incidence of PTTS varies according to preoperative pain, pain intensity, sex, and types of procedure. However, little is known about the effect of the type of anesthesia to postthoracotomy pain.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients undergo elective thoracotomy of lung surgery

排除标准

  • emergency operation age under 18 years patients with unstable hemodynamics

研究组 & 干预措施

Group I, Group II

Group I: anesthetized with TIVA (Propofol + Remifentanil)

Group II: anesthetized with inhalation (sevoflurane)

干预措施: propofol, remifentanil, sevoflurane (Drug)

结局指标

主要结局

Incidence of pain

时间窗: 3 and 6 months later after operation

次要结局

  • pain characters(3 and 6 months later after operation)

研究者

申办方类型
Other

研究点 (1)

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