The role of nutritional support of human immunodeficiency virus (HIV) infected patients on antiretroviral treatment

Completed

• Conditions: Human immunodeficiency virus (HIV) infection; Infections and Infestations; Human immunodeficiency virus (HIV)

• Registration Number: ISRCTN32453477
• Lead Sponsor: niversity of Copenhagen (Denmark)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10-04
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

1. HIV-infected adults (aged greater than or equal to 18 years, either sex) commencing ART
2. Living within approximately 50 km from Jimma
3. Consenting to participate

Exclusion Criteria

1. Pregnant or lactating
2. Terminally ill from HIV or other serious condition
3. Patients who may not be able to consume RUSF due to extensive oral lesion
4. Patients with nutritional oedema

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change over the first three months in:<br>1. Lean body mass as assessed using deuterium dilution test<br>2. Grip strength as assessed using a dynamometer<br>3. Physical activity assessed using a combined accelerometer and heart rate monitor

Secondary Outcome Measures

Name	Time	Method
Measured after three months:<br>1. ART drug levels<br>2. HIV load and CD4 counts<br>3. Adherence to ART and quality of life<br>4. IGF-1