IRCT20220907055908N1
Recruiting
Phase 3
Investigating the anti-inflammatory effect of colchicine in patients undergoing coronary artery bypass graft (CABG) in Semnan kosar hospital in 1401: A randomized clinical trial
Semnan University of Medical Sciences0 sites90 target enrollmentTBD
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease.
- Sponsor
- Semnan University of Medical Sciences
- Enrollment
- 90
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients over 30 years old and under 80 years old
- •patients needing CABG surgery
- •Informed consent
Exclusion Criteria
- •patients should have contraindications to colchicine or atorvastatin
- •patients with a history of severe liver diseases
- •patients who have creatinine clearance less than 50\.
- •patients with a history of atrial fibrillation or atrial flutter or 2nd and 3rd\-degree heart block
- •patients with autoimmune diseases or a history of taking immunosuppressive drugs in the last 1 month
- •patients with heart failure Ejection Fraction \< 35%
- •patients with a history of muscle conflicts
- •patients of taking fibrate drugs
- •patients with leukopenia or active infection
- •patients with acute coronary syndrome
Outcomes
Primary Outcomes
Not specified
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