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Clinical Trials/NCT06007859
NCT06007859
Completed
Not Applicable

Influence of Section Orientation of Ultrasound Shear Wave Elastography on the Measurement of Thyroid Nodules Stiffness

Ma Zhe1 site in 1 country67 target enrollmentFebruary 1, 2022
ConditionsThyroid Nodules

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Thyroid Nodules
Sponsor
Ma Zhe
Enrollment
67
Locations
1
Primary Endpoint
elastic modulus values
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The objective of this observational study was to evaluate the effect of transverse and longitudinal sections on the measurement of thyroid nodule stiffness by shear wave elastography. The main questions it aims to answer are: (i) to compare the diagnostic efficacy of different section orientations of shear wave elastography for the diagnosis of benign and malignant thyroid nodules; (ii) to analyze the correlation between the two orientations of transverse and longitudinal sections of shear wave elastography; and (iii) to compare the reliability and consistency of the two orientations of transverse and longitudinal sections of shear wave elastography for the diagnosis of thyroid nodules. Participants will undergo routine ultrasound examination of the thyroid gland and shear wave elastography, and the measured modulus of elasticity of the nodules in both transverse and longitudinal sections will be recorded.

Registry
clinicaltrials.gov
Start Date
February 1, 2022
End Date
November 30, 2022
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Ma Zhe
Responsible Party
Sponsor Investigator
Principal Investigator

Ma Zhe

Director of Ultrasound

Qianfoshan Hospital

Eligibility Criteria

Inclusion Criteria

  • All patients underwent preoperative shear-wave elastography ultrasonography; thyroid nodules ranged from 3 to 20 mm in size; all nodules underwent puncture biopsy or surgery to obtain pathologic results.

Exclusion Criteria

  • Unavailability of pathology results for various reasons; poor quality of ultrasound images; missing data.

Outcomes

Primary Outcomes

elastic modulus values

Time Frame: The elastic modulus values of different sections were recorded immediately after the patients underwent routine ultrasound and shear wave elastography and the recorded results were saved.

the maximum value of elastic modulus (Emax) and the average value of elastic modulus (Emean) of benign and malignant nodules in both longitudinal and transverse sections

Study Sites (1)

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