Subarachnoid Block Versus Ultrasound Guided Transversalis Fascia Plane Block for Postoperative Analgesia of Inguinal Hernia Repair in Adults

Not Applicable

Recruiting

• Conditions: Postoperative Analgesia of Inguinal Hernia Repair in Adults
• Interventions: Drug: bupivacaine injection by ultrasound guided transversalis fascia plane block

• Registration Number: NCT06219837
• Lead Sponsor: Cairo University

Brief Summary

The aim of our study is to investigate the effect of the ultrasound guided transversalis fascia plane block on the postoperative opioid consumption as a part of multimodal analgesia in patients undergoing inguinal herniorrhaphy under spinal anesthesia.

Detailed Description

The aim of our study is to investigate the efficacy of the ultrasound-guided transversalis fascia plane block as a postoperative analgesia as a part of multimodal analgesia in patients undergoing inguinal herniorrhaphy under spinal anesthesia.

The ultrasound (US)-guided transversalis fascia plane (TFP) block was first described by Hebbard in 2009. A local anesthetic (LA) injected between the transversus abdominis muscle, and its deep investing fascia will block the anterior and the lateral branches of the T12 and L1 nerves (4). The efficacy of this block has been demonstrated in iliac crest bone graft harvesting, caesarean section and inguinal herniorrhaphy

Study Timeline

• Study First Submitted: 2023-06-06
• Study Start: 2023-08-01
• Status Verified: 2024-01
• Study First Submitted QC: 2024-01-12
• Last Update Submitted: 2024-01-12
• Study First Posted: 2024-01-23
• Last Update Posted: 2024-01-23
• Primary Completion: 2024-08
• Study Completion: 2024-10

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients undergoing inguinal herniorrhaphy.
• Patients 18-60 years.
• ASA I and II.
• Both sexes.
• Having no contraindication for spinal anesthesia or TFP block.

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Exclusion Criteria

• Refusal of regional anesthesia.
• Infection in the back or at the site of injection for TFP block.
• INR > 1.5.
• Platelet count < 80000 per microliter of blood.
• Patients known to be allergic to amide local anesthetics.
• BMI greater than 35 kgm_2.
• Opioid addiction.
• Have communication problems that may hinder the assessement of pain postoperative.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
20 ml of 0.9% normal saline solution	bupivacaine injection by ultrasound guided transversalis fascia plane block	he patient in this arm will receive 20 ml of 0.9% normal saline solution by ultrasound guided transversalis fascia block for inguinal herniorraphy
bupivacaine group	bupivacaine injection by ultrasound guided transversalis fascia plane block	the patient in this arm will receive 20 ml of 0.25% bupivacaine injection by ultrasound guided transversalis fascia block for inguinal herniorraphy

Primary Outcome Measures

Name	Time	Method
The total amount of postoperative morphine consumption during the first 24hrs postoperative.	First 24 hours postoperative	The patients will be evaluated regarding the first demand to rescue analgesia postoperatively. The pain will be assessed by the VAS score. It will be performed in the immediate post-operative period every 15 min for the first 60 min, 2 h, 4 h, 8h, 12h, 18 and 24 h. Breakthrough pain will be defined as VAS \>4 at rest.

Trial Locations

Locations (1)

Faculty of Medicine, Cairo University; 🇪🇬 Cairo, Giza, Egypt