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临床试验/NCT07349953
NCT07349953已完成不适用

Estimation of Correlation Betweeen Antropometric Characteristics of Children up to 8 Years and Age-based Formulas for Uncuffed Endotracheal Tube in Elective Intubated Children During General Anesthesia

Mother and Child Health Institute of Serbia Dr Vukan Cupic0 个研究点目标入组 103 人开始时间: 2025年7月1日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
103

研究概览

简要总结

The goal of this observational study is to investigate the correlation between anthropometric characteristics, such as finger circumferences, body weight, body height, and body mass index, and age-based formulas for uncuffed tube size in pediatric patients up to 8 years of age.

详细描述

Patients who met inclusion criteria entered the study. All included patients were premedicated with midazolam 0.1mg/kg IV 30 minutes before general anesthesia. Induction: propofol 2,5mg/kg IV, rocuronium 0,6mg/kg IV, fentanyl 3mcg/kg IV; maintenance: sevoflurane 1vol% - 2vol%, fentanyl 3mcg/kg IV as needed. reversion of neuromuscular block was achieved using sugammadex. Trachea was intubated using direct laryngoscopy. Intubation performed one anesthesiologist with more than 10 years of clinical experience in pediatric anesthesia. Initial choice of endotracheal tube (ET) was based on the size of little finger. Proper position of ET was confirmed with chest auscultation, capnography and capnometry. If placing ET was difficult or air leak was not detected using inspiratory pressure > 25cmH2O,ET was replaced with 0,5mm smaller one. If there was air leak using inspiratory pressure < 10 mmHg ET was replaced with 0.5mm bigger one. All children were ventilated using protective strategy. After intubation, measures were made:

  1. Finger's circumference was measured with flexible ruler tape (in millimeters). The tape was wrapped around the base of the finger. Circumferences of index finger, middle finger, ring finger and small finger were documented for each hand.
  2. Data of body weight, body height and body mass index were taken from patients history.
  3. Sizes of used endotracheal tubes were documented.
  4. Calculations of ET tube size using age based formulas were made:

for children over 2 years ID (mm) = god/4+4 for children under 2 years of age ODcal (mm) = 0,00223x age(days)+4.88

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
1 Day 至 8 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Age up to 8 years of age;
  • Children without congenital and acquired anomalies of the trachea;
  • Children in whom tracheal intubation is planned as part of the anesthesia plan

排除标准

  • Age over 8 years of age;
  • The presence of congenital and acquired anomalies of the trachea;
  • Children who are already intubated; and failure to obtain informed consent

研究者

发起方
Mother and Child Health Institute of Serbia Dr Vukan Cupic
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ana Mandras

MD, PhD

Mother and Child Health Institute of Serbia Dr Vukan Cupic

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