A study of appropriate fluid volume for resuscitation (evaluation of stroke volume variation under spontaneous respiration) - A study of appropriate fluid volume for resuscitation

Patients (n= 37) with septic shock who were fitted with FloTrac sensor. The mean of lactate value, IVC diameters, SVV values during initial fluid resuscitation vs. "stable svv" were 6.0 vs.1.8 mmol/L, 11 vs. 19 mm and 18.6 vs.8.8%, respectively (p < 0.001). Fluctations in SVV curves calculated by fast Fourier transformation resulted in a Lorentzian spectrum. The amplitude of all curves peaked at frequency = 0 and became significantly lower when "SVV stable" than during fluid therapy (1.3 vs.3.7%; p < 0.001).