Optimal Fluid Resuscitation for Trauma Patients

Completed

• Conditions: Trauma

• Registration Number: NCT00527098
• Lead Sponsor: University of Miami

Brief Summary

The purpose of this study is to determine if the overall fluid requirements for the first 24 hours after admission will be reduced with Hextend versus a standard of care crystalloid resuscitation fluid.

Detailed Description

Following severe multi-system traumatic injury, the first 24 hours of standard resuscitation fluid will be either Hextend or crystalloid depending upon attending preference. No tests or interventions will be performed for research purposes.

Data will be collected prospectively from patient medical records and attending clinicians to monitor fluid requirements, hemodynamics and outcome.

Study Timeline

• Study First Submitted: 2007-09-06
• Study First Submitted QC: 2007-09-06
• Study First Posted: 2007-09-10
• Study Start: 2007-10
• Primary Completion: 2010-07
• Study Completion: 2010-07
• Results First Submitted: 2011-04-01
• Results First Submitted QC: 2011-04-01
• Results First Posted: 2011-05-04
• Status Verified: 2013-02
• Last Update Submitted: 2013-02-20
• Last Update Posted: 2013-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 119

Inclusion Criteria

• Greater than or equal to 18 years old and less than 65 years old
• Admission with multi-system traumatic injury
• Admission to the intensive care unit

Exclusion Criteria

• Less than 18 or greater than 65 years old
• Pregnant or lactating
• No fluid resuscitation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality	From hospital arrival up to an average of 3.5 weeks

Trial Locations

Locations (1)

Ryder Trauma Center; 🇺🇸 Miami, Florida, United States