Cohort study on the effects of aging in acquired brain injury patients

Recruiting

• Conditions: niet-aangeboren hersenletsel (traumatisch hersenletsel, CVA en SAB); acquired brain injury; 10042258

• Registration Number: NL-OMON52212
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 715

Inclusion Criteria

- acute acquired brain injury (ABI) (traumatic brain injury, subarachnoidal
hemorrhage, cerebrovascular accident
- ABI more than 5 years ago
- ABI at the age of 25 years or older
- current age between 50- 67 years
- able to complete questionnaires independently
- for case-control study: results of an earlier neuropsychological assessment,
that has been done in the non-acute but confined phase after ABI; between 3 and
12 months after injury must be availabe.

Exclusion Criteria

- second ABI for which patient was admitted
- psychiatric disease for which the patient is treated
- alcohol and drug abuse
- language barriers or illiteracy limiting filling out questionnaires

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cohort study:<br /><br>The percentage of patients experiencing the ABI-effect. Also, a 95% confidence<br /><br>interval of this prevalence will be calculated.<br /><br><br /><br>Case-control study:<br /><br>The significant difference in cognitive functions between the patient groep and<br /><br>the healthy controls.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Cohort study:<br /><br>- The degree of decline in participation<br /><br>- The different areas in which decline in participation is experienced.<br /><br>- Scores on questionnaires<br /><br>- Need of care for patients<br /><br><br /><br>Case-control study:<br /><br>- Comparison of scores in two points in time (first and second NPA)<br /><br>- Performance on neuropsychological tests in different cognitive domains</p><br>