Monitoring Hypertensive Patients's Cerebral Oxygen Saturation
Completed
- Conditions
- Surgical Complications From General AnesthesiaHypertensionCerebral AnoxiaCerebral Ischemia
- Registration Number
- NCT02147275
- Lead Sponsor
- Huazhong University of Science and Technology
- Brief Summary
The purpose of this study is to determine whether there is a significant decrease in cerebral oxygen saturation in hypertensive patients undergoing major abdominal surgery and their correlation with standard monitoring parameters.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 41
Inclusion Criteria
- patients have hypertension more than 3 year,whether well-controlled or uncontrolled,
- scheduled for major abdominal surgery for at least 2 h
- under general anesthesia
- American Society of Anesthesiologists（ASA）physical status : II ~ III
- Age > 30
Exclusion Criteria
- pre-existing cerebral pathology for example episodes of cerebral ischemia or stroke;
- ASA physical status >IV
- hepatic failure
- renal failure
- preoperative Mini-Mental State Examination (MMSE) score less than 24
- a history of cardiovascular surgery or craniotomy
- cardiac failure
- respiratory failure
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method decreases in cerebral oxygen saturation (rSO2) during the surgery every 5 minutes throughout the surgery
- Secondary Outcome Measures
Name Time Method Change from baseline in Mini-Mental State Exam (MMSE) perioperative period Baseline, 4 day after surgery
Trial Locations
- Locations (1)
Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
🇨🇳Wuhan, Hubei, China