Noninvasive Assessment of Cerebral Oxygenation and Cardiac Function in Patients With Neurovascular Diseases
Completed
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal
- Registration Number
- NCT02991157
- Lead Sponsor
- National Institute of Mental Health and Neuro Sciences, India
- Brief Summary
This prospective observational study will assess the regional cerebral oxygen saturation and cardiac output non-invasively in patients with subarachnoid hemorrhage during nimodipine administration for the prevention/management of cerebral vasospasm.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- aneurysmal subarachnoid hemorrhage
- potential or actual cerebral vasospasm
Exclusion Criteria
- non-aneurysmal subarachnoid hemorrhage
- outside the 4-21 day window after ictus
- peripheral deoxygenation
- contraindication for nimodipine administration
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in the cerebral oxygen saturation percentage measured using near infrared spectroscopy technology after administration of nimodipine Change from baseline cerebral oxygen saturation at 30 minutes after administration of nimodipine
- Secondary Outcome Measures
Name Time Method Change in the cardiac output measured using near NICOM technology after administration of nimodipine Change from baseline cardiac output at 30 and 240 minutes after administration of nimodipine unit of measurement will be L/min
Change in the cerebral oxygen saturation percentage measured using near infrared spectroscopy technology after administration of nimodipine Change from baseline cerebral oxygen saturation at 240 minutes after administration of nimodipine
Trial Locations
- Locations (1)
NIMHANS
🇮🇳Bengaluru, India