NCT02147275已完成不适用
Monitoring Cerebral Oxygen Saturation in Hypertensive Patients Undergoing Major Abdominal Surgery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 41
- 试验地点
- 1
- 主要终点
- decreases in cerebral oxygen saturation (rSO2) during the surgery
研究概览
简要总结
The purpose of this study is to determine whether there is a significant decrease in cerebral oxygen saturation in hypertensive patients undergoing major abdominal surgery and their correlation with standard monitoring parameters.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients have hypertension more than 3 year,whether well-controlled or uncontrolled,
- •scheduled for major abdominal surgery for at least 2 h
- •under general anesthesia
- •American Society of Anesthesiologists（ASA）physical status : II ~ III
- •Age > 30
排除标准
- •pre-existing cerebral pathology for example episodes of cerebral ischemia or stroke;
- •ASA physical status >IV
- •hepatic failure
- •renal failure
- •preoperative Mini-Mental State Examination (MMSE) score less than 24
- •a history of cardiovascular surgery or craniotomy
- •cardiac failure
- •respiratory failure
结局指标
主要结局
decreases in cerebral oxygen saturation (rSO2) during the surgery
时间窗: every 5 minutes throughout the surgery
次要结局
- Change from baseline in Mini-Mental State Exam (MMSE) perioperative period(Baseline, 4 day after surgery)
研究者
Li Hongyi
Department of Anesthesiology, Tongji Hospital of Tongji Medical College
Huazhong University of Science and Technology
研究点 (1)
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