Cerebral Oximetry to Reduce Peri-operative Morbidity: A Pilot Study

Not Applicable

Completed

• Conditions: Peri-operative morbidity; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12612000539831
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05-22
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1.Adult patients (age > 70 years)
2.Total knee or hip joint replacement, or bowel resection surgery.

Exclusion Criteria

1.Emergency or unplanned surgery.
2.Inability to provide informed consent for participation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of any complication in first five days following surgery.<br><br>Pre-defined Complications:<br>Acute myocardial infarction<br>Cardiac arrest<br>Re-intubation<br>Acute pulmonary oedema<br>Pulmonary embolus<br>Stroke<br>Systemic inflammation<br>Wound infection<br>Unplanned return to operating room<br>Acute renal impairment<br>Unplanned ICU admission<br>Death[5 days]

Secondary Outcome Measures

Name	Time	Method
Incidence of individual specified complications.<br><br>Pre-defined Complications:<br>Acute myocardial infarction<br>Cardiac arrest<br>Re-intubation<br>Acute pulmonary oedema<br>Pulmonary embolus<br>Stroke<br>Systemic inflammation<br>Wound infection<br>Unplanned return to operating room<br>Acute renal impairment<br>Unplanned ICU admission<br>Death[5 days];30-day mortality[30 days];Length of hospital stay[At discharge];Incidence of cerebral desaturation (using cerebral oximeter)<br>Cerebral desaturation is defined as a fall in the cerebral saturation more than 25% below the participant's own baseline. All cerebral saturation data is stored and can be analysed offline.[Intra-operative];Total duration of cerebral saturation < 75% baseline (using cerebral oximeter).<br>Cerebral desaturation is defined as a fall in the cerebral saturation more than 25% below the participant's own baseline. All cerebral saturation data is stored and can be analysed offline.[Intra-operative]