Comparing the effects of nebulized salbutamol epinephrine and 5 hypertonic saline on lowering theseverity of symptoms in infant
Phase 3
Recruiting
- Conditions
- Acute bronchiolitis.Acute bronchiolitis
- Registration Number
- IRCT20201101049210N1
- Lead Sponsor
- Gorgan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
pediatric respiratory severity score>=4
history of lower respiratory tract infections
wheezing,cough,cyanosis,spo2<90, fever
age 2-24 month
Exclusion Criteria
drug reaction to salbutamol or epinephrine or hypertonic salin
history of chronic cardiopulmonary disease
preterm labor
histroy of admision in age 0-2 month
history of treatment with bronchodilator agents
history of corticosteroid administration
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary Outcome: Clinical signs including severity of respiratory distress, wheezing, skin color, general mood, respiratory rate, body temperature, and lung murmur. Timepoint: Before the intervention and 24 and 48 hours after the intervention. Method of measurement: Based on the score obtained from the pediatric respiratory severity score and observation.
- Secondary Outcome Measures
Name Time Method The length of hospital stay is the number of days a patient receives medication, parenteral fluid, and oxygen for bronchiolitis. Timepoint: Once at the end of the treatment period. Method of measurement: Count the days the patient receives medication, parenteral fluid, and oxygen for bronchiolitis.