A comparison of continuous inhalation of salbutamol and continuous inhalation of isoproterenol for severe pediatric bronchial asthma: A multicenter, double-blind, randomized study
Not Applicable
- Conditions
- bronchial asthma
- Registration Number
- JPRN-UMIN000001991
- Lead Sponsor
- Dapartment of Pediatrics, Jikei University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with any of the following conditions are excluded: patients with fever (higher than 38.5 centidegree); patients who took an antipyretic drug within six hours; patients with underlying diseases, such as chronic lung disease or cyanotic heart disease, or systemic disease that may cause wheezing; patients with a past history of arrhythmia caused by a beta2-agonist; patients with croup syndrome; patients with suspected foreign-body aspiration; patients with bronchiolitis; patients with pneumonia requiring antibiotic therapy; patients with lobular atelectasis; and patients requiring intratracheal intubation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The degree of change in the mPI scores between baseline and 3 hours after the start of therapy
- Secondary Outcome Measures
Name Time Method 1) The degree of change in the mPI score between baseline and 12 hours after the start of therapy 2) The degree of change in the respiratory rate between baseline and 3 hours after the start of therapy 3) The degree of change in the heart rate between baseline and 3 hours after the start of therapy 4) The degree of improvement at 3 and 12 hours after the start of therapy