Excimer Light in Psoriasis
Not Applicable
Completed
- Conditions
- Psoriasis
- Interventions
- Device: Excimer light
- Registration Number
- NCT05283876
- Lead Sponsor
- Cairo University
- Brief Summary
The aim of this study is to determine the standard tissue levels of SP and its receptor in lesional skin of psoriasis patients in both developing and stationary stages before and after excimer light therapy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Type of Psoriasis: plaque psoriasis.
- Less than 10% surface area.
Exclusion Criteria
- Erythrodermic psoriasis
- Pustular psoriasis
- Topical treatment for psoriasis for the past 2 weeks.
- Systemic retinoids in the last 2 years.
- Systemic treatments (including any drugs that affect SP level as Aprepitant) in the last 3 months.
- Contraindications to excimer light therapy (history of skin malignancy or precancerous conditions like xeroderma pigmentosum or photosensitivity)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Stable psoriasis Excimer light - Active psoriasis Excimer light -
- Primary Outcome Measures
Name Time Method Excimer laser efficiency in active and stable psoriasis through study completion, an average of 6 months Determine the clinical improvement using Local psoriasis severity index
Excimer laser efficiency on neurogenic inflammation through study completion, an average of 6 months level of affection of the neurogenic inflammation in psoriasis lesions after using Excimer light therapy. Determine substance P and its receptor levels before and after therapy.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Kasr Al Ainy Faculty of medicine
🇪🇬Cairo, Egypt