Determination of the Antibacterial Effect of Biodentine in vivo - Identification of Polybacterial 16S rRNA Genes in Caries Samples by T-RFLP and Direct Sequencing

Septodont0 个研究点目标入组 10 人开始时间: 2016年9月15日最近更新: 2024年8月19日

适应症

试验速览

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•Primary carious dentine lesions at 2 (or more) molars or premolars which are not in contact (e.g. in different sextants), indication to perform a stepwise caries therapy irrespective of the study
•-clinical Picture: according to the International Caries Detection and Assessment System (ICDAS) 4, 5 or 6
•-complete isolation by rubberdam is possible
•-radiographic extension up to the inner half of the dentine (R4-lesions)
•-no clinical symptoms of the study teeth
•-positive sensitivity of the study teeth
•in cases of carious lesion(s) or insufficient restoration margins in proximity of one of the study cavities: clinically acceptable restoration before trial conduction starts
•signed informed consent

•cases of known intolerance of dental materials (or one of their ingrediences) applied in the study course
•reasons which make it unlikely to be able to determine the outcome or probable consequences of the study (e.g. alcoholism, mental disability)
•pregnancy, breastfeeding
•evidence that keeping treatment appointments will not be able

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