Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment III) - 3
- Conditions
- Heroin DependenceOpioid-Related Disorders
- Registration Number
- NCT00000328
- Lead Sponsor
- University of Colorado, Denver
- Brief Summary
The purpose of this study is to compare the clinical efficacy of the buprenorphine/naloxone combination tablet to methadone for opioid maintenance treatment.
- Detailed Description
S/A brief "Summary for the Public"
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Individuals must be at least 18 years of age, currently opioid dependent and meet FDA criteria for narcotic maintenance treatment. Co-morbid substance abuse or dependence disorders may also be present. Individuals must be healthy despite drug dependency.
Individuals with evidence of an active Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) Axis I psychiatric disorder (e.g. psychosis, manic-depressive illness, organic psychiatric disorders), significant medical illness (e.g. liver or cardiovascular disease) or pregnant female subjects are excluded from study participation.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Opioid agonist rating Opioid antagonist rating Compliance Addiction Severity Index (ASI) Composite Score Rating Drug use Retention Medication identification
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Colorado Health Sciences Center
🇺🇸Denver, Colorado, United States