Discharge Opioid Education to Decrease Opioid Use After Cesarean
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 196
- Locations
- 2
- Primary Endpoint
- Opioid Use
Study Overview
Brief Summary
Background: The number of opioid overdose deaths in the United States has quadrupled in 15 years, a dramatic manifestation of the current opioid abuse epidemic. This rise parallels a sharp increase in the amount of legal prescription opioids dispensed. The abundance of prescription opioids available is a primary pathway for opioid abuse and diversion and higher opioid use after surgery has been associated with an increased risk of chronic opioid use. Reducing the amount of opioid used after cesarean delivery may decrease the risk of chronic opioid use and will help towards better estimating and reducing the amount of opioids prescribed at discharge.
Objective: To to compare discharge opioid education to standard care to ascertain whether opioid education reduces opioid use after hospital discharge
Detailed Description
Background: The number of opioid overdose deaths in the United States has quadrupled in 15 years, a dramatic manifestation of the current opioid abuse epidemic. This rise parallels a sharp increase in the amount of legal prescription opioids dispensed. The abundance of prescription opioids available is a primary pathway for opioid abuse and diversion and higher opioid use after surgery has been associated with an increased risk of chronic opioid use. Reducing the amount of opioid used after cesarean delivery may decrease the risk of chronic opioid use and will help towards better estimating and reducing the amount of opioids prescribed at discharge.
Objective: To to compare discharge opioid education to standard care to ascertain whether opioid education reduces opioid use after hospital discharge
Preliminary Data: Our soon to be published study (Obstetrics & Gynecology Journal) found that 30% of women used all their opioids after discharge for cesarean delivery because they "were following directions" and not because they had pain.
Enrollment & Randomization
Enrollment
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 45 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Women 18-45 years old
- •Women undergoing cesarean delivery at VUMC
Exclusion Criteria
- •Major post-surgical complications:
- •cesarean hysterectomy, bowel or bladder injury, reoperation, ICU admission, wound infection or separation
- •Chronic opioid use: Taking buprenorphine during pregnancy, taking an opioid for > 7 days during pregnancy.
- •Women who do not speak English
Outcomes
Primary Outcomes
Opioid Use
Time Frame: 6 weeks postpartum
Median number of tablets of hydrocodone-acetaminophen used after hospital discharge
Secondary Outcomes
- Disposed of Opioids Correctly(6 weeks postpartum)
- Analgesic Quiz Score(6 weeks postpartum)
- Additional Prescriptions(6 weeks postpartum)
Investigators
Sarah Osmundson
Assistant Professor, Ob/Gyn
Vanderbilt University Medical Center