NCT05863858已完成3 期
High Eradication Rate of Helicobacter Pylori Infection With Moxifloxacin-Based Triple Therapy in Comparison With Levofloxacin-Based Sequential Therapy: Randomized Controlled Trials
Iyad Naeem Muhammad, PhD2 个研究点 分布在 1 个国家目标入组 162 人开始时间: 2020年6月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 162
- 试验地点
- 2
- 主要终点
- Helicobacter pylori status one month after treatment.
研究概览
简要总结
The main objective of the study is to compare the effectiveness of moxifloxacin triple therapy with levofloxacin-based sequential therapy in terms of eradication rate, safety, and patient compliance.
详细描述
Patients who were confirmed to be positive for Helicobacter Pylori infection were randomly assigned to the eradication treatments. At four weeks after completion of eradication therapy, H. pylori tests were performed with a Stool antigen test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Successful isolation of H. pylori from the patient, and
- •patients of at least 18 years of age.
排除标准
- •age under 18 years
- •presence of clinically significant associated conditions (insulin-dependent diabetes mellitus, gastrointestinal bleeding, neoplastic diseases, coagulation disorders, and neurologic, metabolic, hematological or endocrine hepatic, cardiorespiratory, or renal diseases),
- •previous gastric surgery,
- •allergy to any of the drugs used in the study, and (5) pregnancy or breastfeeding.
结局指标
主要结局
Helicobacter pylori status one month after treatment.
时间窗: One month after finishing with therapy.
Helicobacter pylori status (positive or negative), will be measured by stool test, one month after finishing with therapy.
次要结局
- Adverse effects of therapy in both groups in treatment of Helicobacter pylori infection.(One month after finishing with therapy.)
- Compliance of patients in both therapy groups in treatment of Helicobacter pylori infection.(One month after finishing with therapy.)
研究者
Iyad Naeem Muhammad, PhD
Associate Professor
University of Karachi
研究点 (2)
Loading locations...
相似试验
已完成
4 期
Comparison of Conventional Triple Therapy Versus Sequential Therapy for H. Pylori in Peptic Ulcer Disease: Prospective Randomized TrialHelicobacter Infected PatientsNCT01418300Jun-Won Chung159
Unknown
4 期
Concomitant Therapy of H. PyloriGastritis, Gastric Ulcer, and Duodenal UlcerNCT01922765The Catholic University of Korea540
招募中
4 期
Vonoprazan Hp Dual or Triple Eradication RegimesHelicobacter PyloriNCT05345210Xijing Hospital of Digestive Diseases500
已完成
3 期
Triple Therapy Versus Levofloxacin-based Therapy for Helicobacter Pylori Eradication in Mexico.Helicobacter Pylori GastritisNCT02726269Asofarma de México S.A de C.V.230
Unknown
4 期
Increased Re-eradication Rate of Helicobacter Pylori by Adding N-acetylcystein or Metronidazole to the Triple TherapyBacterial Infection Due to Helicobacter Pylori (H. Pylori)NCT01572597Buddhist Tzu Chi General Hospital120