Effectiveness of whey peptide and ripening extract of hop for Japanese patients of mild Alzheimer's disease

Not Applicable

• Conditions: Patients with mild Alzheimer' s disease

• Registration Number: JPRN-UMIN000031649
• Lead Sponsor: Department of Psychiatry, Juntendo University, Faculty of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-03-09
• Study Completion: 2020-12-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

Patients with milk allergy (whey)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Estimating for effectiveness of ripening extract of hop and whey peptide containing high concentration of dipeptide (Trp-Tyr) for Japanese patients with mild Alzheimer's disease. 0W (Before); general blood test (including peripheral inflammation markers and phenotype of ApoE), psychological assessments (ADAS-Jcog, MMSE, POMS2) 12W; general blood test (including peripheral inflammation markers and phenotype of ApoE), psychological assessments (ADAS-Jcog, MMSE, POMS2) and SPECT 24W; general blood test (including peripheral inflammation markers and phenotype of ApoE), psychological assessments (ADAS-Jcog, MMSE, POMS2) 36W; general blood test (including peripheral inflammation markers and phenotype of ApoE), psychological assessments (ADAS-Jcog, MMSE, POMS2)

Secondary Outcome Measures

Name	Time	Method
Measurement of the frequencies for tolerance of ripening extract of hop (bitter taste) and whey peptide containing high concentration of dipeptide (Trp-Tyr) (abdominal bloating) for Japanese at 12W, 24W and 36W.