NCT03657017招募中不适用
PET/MR in Locally Advanced Nasopharyngeal Carcinoma
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Multiparametric PET/MRI-based radiomics nomograms for locally advanced nasopharyngeal carcinoma
研究概览
简要总结
PET/MR in Locally Advanced Nasopharyngeal Carcinoma
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- — 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with newly histologically confirmed non-keratinizing carcinoma.
- •Tumor staged T1-4N0-3M0 （according to the 8th AJCC staging system）
- •Performance status: KPS>70
- •With normal liver function test (ALT, AST <1.5ULN)
- •Renal: creatinine clearance >60ml/min
- •Without hematopathy,marrow: WBC >4*109/L, HGB>80G/L, and PLT>100*109/L.
- •Written informed consent
排除标准
- •Adenocarcinoma
- •Prior malignancy (except adequately treated carcinoma in-situ of the cervix or · basal/squamous cell carcinoma of the skin)
- •Previous chemotherapy or radiotherapy (except non-melanomatous skin cancers outside the intended RT treatment volume)
- •Patient is pregnant or lactating
- •Any severe intercurrent disease, which may bring unacceptable risk or affect the compliance of the trial, for example, unstable cardiac disease requiring treatment, renal disease, chronic hepatitis, diabetes with poor control (fasting plasma glucose >1.5×ULN), or emotional disturbance.
研究组 & 干预措施
PET/MR
Other
Patients are examined with PET/MR.
干预措施: PET/MR (Diagnostic Test)
结局指标
主要结局
Multiparametric PET/MRI-based radiomics nomograms for locally advanced nasopharyngeal carcinoma
时间窗: From day 1 of chemotherapy to the date of the event, a minimum follow-up of 3 years.
Radiomics-based prognostic model by PET/MRI
次要结局
- Prediction model of the efficiency of treatment in locally advanced nasopharyngeal carcinoma(about 4 years (all of patients complete treatment))
研究者
Chen Xiaozhong
Clinical Professor
Zhejiang Cancer Hospital
研究点 (1)
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