Transversus Abdominis Plane Blocks for Patients Undergoing Robotic Gynecologic Oncology Surgery: A Prospective Randomized, Double-blind, Placebo-controlled Trial

University of Wisconsin, Madison1 site in 1 country75 target enrollmentSeptember 2011

ConditionsGynecologic Cancer Post-operative Pain

InterventionsBupivicaine Placebo

DrugsBupivicaine Placebo

Overview

Phase: Phase 2
Intervention: Bupivicaine
Conditions: Gynecologic Cancer
Sponsor: University of Wisconsin, Madison
Enrollment: 75
Locations: 1
Primary Endpoint: 24 Hour Post Operative Opioid Consumption, Converted to Intravenous Morphine Equivalents
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

This study is a single-center, randomized, placebo-controlled, double-blind clinical trial. The purpose of this study is to evaluate the impact of pre-operative transverses abdominis plane (TAP) blocks on post-operative analgesia in patients undergoing robotic surgery for gynecologic cancers.

Registry

clinicaltrials.gov

Start Date

September 2011

End Date

March 2013

Last Updated

6 years ago

Study Type

Interventional

Study Design

Parallel

Sex

Female

Investigators

Sponsor

University of Wisconsin, Madison

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patients undergoing robotic-assisted surgery under the care of the Division of Gynecologic Oncology at UWHC.
•Patients must be ≥18 years old.
•Patients must be English speaking.
•Patients must have the ability to understand visual and verbal pain scales.
•ASA physical status 1-3.

Exclusion Criteria

•Known allergy to local anesthetics.
•Immunocompromised.
•Known history of opioid dependence, as available within the medical record and standard of care pre-operative work-up.
•Known history of chronic pain disorders.
•Pregnancy or lactation.
•Patient is a prisoner or incarcerated.
•Significant liver disease that would inhibit prescription of opioids.