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临床试验/NCT03766451
NCT03766451Unknown不适用

Noninvasive Assessment of Intravascular Volume Status for Postoperative Patients: The Correlation Between Internal Jugular Vein/Common Carotid Artery Cross-Sectional Area Ratio and the Inferior Vena Cava Diameter

Beni-Suef University1 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2018年11月10日最近更新:
适应症

试验速览

阶段
不适用
入组人数
35
试验地点
1
主要终点
The correlation between (Internal Jugular Vein/Common Carotid Artery Cross-Sectional Area Ratio),and Inferior Vena Cava Diameter by using ultrasound

研究概览

简要总结

Ultrasound measurements of the inferior vena cava (IVC) have been proposed as a noninvasive tool to help guide fluid management. Well-established correlations exist between respiratory cycle-induced changes in IVC diameter and C entral Venous Pressure (CVP) . Beyond providing an estimate of CVP, the caval index, or percentage collapsibility of the IVC , has been proposed as a predictor of preload reserve. This noninvasive rapid measurement of CVP is especially important in critical care settings. It can help in differentiating hypovolemic, septic and cardiogenic shock. Changes in volume status will be depicted by change in the diameter of the IVC .

However, the validity and reliability of sonographic assessment of the inferior vena cava have been matters of controversy, and its applicability has been shown to be limited by technical difficulties. Recent study has shown a significant relationship between the internal jugular vein/common carotid artery (IJV/CCA) cross-sectional area ratio and CVP in pediatric burn patients .

详细描述

Type and Site of The study:

This study will be be done at Beni-Suef university hospital ,Surgical Intensive Care Unit (SICU) after approval of the local ethics and research committee and anesthesia department of Beni- Suef University.

DATE AND PERIOD OF THE STUDY:

The study will be done between NOV. 2018 and Nov. 2019

Patients will be included:

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • ASA physical status I and II
  • Patients who are able to breathe spontaneously and lay supine post-operative.
  • Patients who had CVP catheter (subclavian or internal jugular vein)

排除标准

  • 1- Chronic obstructive or restrictive pulmonary disease. 2-Significant cardiac disease 3-Significant hepatic disease 4-Renal impairment ( creatinine >2 mg/dl). 5- BMI ˃ 30 kg/m2 6- Pneumothorax or mediastinal masses. 7- mechanical ventilation or coming with tracheostomy. 8- defect at the site of sonography. 9- Pregnancy. 10- Instability of vital signs 11- Unwillingness to participate 12- sepsis or septic shock. 13- neurosurgical interventions

结局指标

主要结局

The correlation between (Internal Jugular Vein/Common Carotid Artery Cross-Sectional Area Ratio),and Inferior Vena Cava Diameter by using ultrasound

时间窗: immediately upon admission to surgical intensive care unit and after acchieving cvp above 8 cmh2o by saline infusion (10 ml/kg) average 3 hours after admission

The correlation between (Internal Jugular Vein/Common Carotid Artery Cross-Sectional Area Ratio),and Inferior Vena Cava Diameter by using ultrasound

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hebatullah Negm Eldeen Abd El Azeem

Assistant lecturer

Beni-Suef University

研究点 (1)

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