Determination of equal analgesic doses between inhaled metoxyflurane and intravenous fentanyl using ice-water test in volunteers.
Phase 1
- Conditions
- Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]Experimental pain model (cold pressor test – CPT) will be used to determinate equipotent doses of inhaled metoxyflurane vs. intravenous fentanyl.
- Registration Number
- EUCTR2018-003939-30-NO
- Lead Sponsor
- Oslo University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
The volunteers should be in good health and not have any chronic illness.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 12
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range 0
Exclusion Criteria
No use of pain medication and complementary medicine the last 2 days before a session. Previous substance abuse, pregnancy and known allergies or serious side effects to opioids or metoxyflurane.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method