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Clinical Trials/NCT03239444
NCT03239444
Completed
Phase 1

Visualization of Human Cardiovascular Anatomy With Foresight Intracardiac Echocardiography (ICE) System

Conavi1 site in 1 country13 target enrollmentApril 24, 2017

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Atrial Fibrillation
Sponsor
Conavi
Enrollment
13
Locations
1
Primary Endpoint
Evaluation of the study device for guiding transseptal puncture in order to gain access to the left atrium of the heart during an ablation procedure in patients suffering with atrial fibrillation.
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This study will evaluate the efficacy of the Foresight Intracardiac Echocardiography system ,with improved image quality, in guiding trans-septal punctures during atrial fibrillation ablation procedures.

Detailed Description

The study will recruit 10 patients at a single center.

Registry
clinicaltrials.gov
Start Date
April 24, 2017
End Date
December 24, 2018
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Conavi
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient is at least 18 years old.
  • Patient is undergoing an atrial fibrillation ablation procedure.
  • Patient has a transesophageal echocardiogram (TEE) within the 48 hours prior to ablation procedure to rule out left atrial thrombus.
  • Patient provides informed, written consent for participation in the study.

Exclusion Criteria

  • Patients in whom placement of an ICE catheter in the right atrium for adequate atrial visualization is not technically feasible (as evaluated and determined by the physician/study investigator performing the procedure).
  • Patients in whom transseptal puncture is relatively contraindicated.
  • Patients in whom left atrial clot or dense spontaneous contrast is identified on TEE, which would increase thromboembolic risk.
  • Women of child bearing potential, in whom pregnancy cannot be excluded.
  • Patients unable to grant informed, written consent for participation in the study.

Outcomes

Primary Outcomes

Evaluation of the study device for guiding transseptal puncture in order to gain access to the left atrium of the heart during an ablation procedure in patients suffering with atrial fibrillation.

Time Frame: For each patient, the individual physician satisfaction survey will be completed on the day of the procedure.

The ability of the study device to identify the atrial septum during transseptal puncture will be evaluated by the physician on the day of the procedure and captured in the individual case report form. This will be based on the objective finding of whether the transseptal puncture was performed (Yes or No) under study device guidance. This information will be gathered for each patient in the individual case report form and presented qualitatively and as quantitative measures (percentage success).

Secondary Outcomes

  • Collection of first human images with Conavi's Foresight System.(An individual physician satisfaction survey will be completed for each case on the day of the procedure.)

Study Sites (1)

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