Study for Optimized protocol of Traditional Chinese Medicine in the Treatment of Chronic Hepatitis B Virus Carriers

Shenzhen Traditional Chinese Medicine Hospital0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

暂无简介。

•1. Patients meet the diagnostic criteria for chronic HBV carriers
•(1) serum HBsAg, HBeAg and HBV-DNA are positive;
•(2) patients are fluped 3 times in one year, whose serum ALT, AST are within the normal range;
•(3) Fibroscan<7.0 kPa or liver histological examination shows no obvious abnormalities.);
•2. The differentiation of traditional Chinese medicine meets spleen-kidney deficiency syndrome;
•3. Aged between 30-65 years, patients have been infected HBV for more than 20 years;
•4. Serum ALT <=40 U/L;
•5. Serum HBV-DNA: >10^5 IU/ml, <10^9 IU/ml;
•6. Histological Knodell HAI<4 score, Ishak<=3 score, or Fibroscan<7.0 kPa;
•7. Patient sign the informed consents and volunteer to participate in this clinical trial.

•1. Patients infect HIV, HCV and HDV;
•2. Patients with metabolic or autoimmune liver disease;
•3. Patients have a history of alcohol abuse or illicit drugs or participate in other clinical trials of hepatitis drugs within 30 days;
•4. Serum ALT and AST levels show abnormality with one years;
•5. Patients are treated with nucleoside or interferon for 24 weeks prior to enrollment;
•6. Inactive HBsAg carriers;
•7. Patients with cirrhosis or patients' AFP are increased;
•8. Pregnant or lactating women;
•9. Patients with mental disease and other serious organ diseases.

发起方

Shenzhen Traditional Chinese Medicine Hospital