A comparison of two different versions of Cognitive Bias Modification (CBM) plus Internet Cognitive Behavioural Therapy (iCBT) for Depression- A Randomised Controlled Trial

Not Applicable

Completed

• Conditions: Depression; Mental Health - Depression

• Registration Number: ACTRN12613000139774
• Lead Sponsor: St Vincent's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-02-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Meet Diagnostic and Statistical Manual of the American Psychiatric Association - 4th edition (DSM-IV) criteria for Major Depressive Disorder, Internet access + printer access, Australian resident, Fluent in written and spoken English.

Exclusion Criteria

Current substance abuse/dependence, Psychotic mental illness (Bipolar or Schizophrenia), Current or planned psychological treatment during study duration, Change in medication during last 1 month or intended change during study duration, use of Benzodiazepines, Suicidal.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in score on the Patient Health Questionnaire-9 (PHQ-9). [Administered at baseline (T1), post-CBM intervention (T2, 1 week after baseline), post iCBT intervention (8-10 weeks after baseline), and at 3 month follow-up (T4).];Change in score on the Beck Depression Inventory - second edition (BDI-II). [Administered at baseline (T1), post-CBM intervention (T2, 1 week after baseline), post iCBT intervention (8-10 weeks after baseline), and at 3 month follow-up (T4).];Change on the Ambiguous Sentence Task (AST). [Administered at baseline (T1) and post-CBM intervention (T2, 1 week after baseline).]

Secondary Outcome Measures

Name	Time	Method
Change in distress on the Kessler-10.[Administered at baseline (T1), post-CBM intervention (T2, 1 week after baseline), post iCBT intervention (8-10 weeks after baseline), and at 3 month follow-up. ];Change on WHO Disability Assessment Scale (WHO-DAS). [Administered at baseline (T1) post iCBT intervention (8-10 weeks after baseline), and at 3 month follow-up (T4).];Change on the Repetitive Thinking Questionnaire (RTQ).[Administered at baseline (T1), post iCBT intervention (8-10 weeks after baseline), and at 3 month follow-up (T4).]; Change on the State Trait Anxiety Inventory (STAI). [Administered at baseline (T1) post iCBT intervention (8-10 weeks after baseline), and at 3 month follow-up (T4).];Change in score on the Clinical Perfectionism Scale (CPS).[Administered at baseline (T1), post iCBT intervention (8-10 weeks after baseline), and at 3 month follow-up (T4).];Change in diagnostic status on the MINI Depression Module[Administered at baseline (T1) and 3-month follow-up (T4). ]